S-(N-PhenethylthiocarbaMoyl)-L-cysteine

Modify Date: 2024-01-12 06:38:35

S-(N-PhenethylthiocarbaMoyl)-L-cysteine structure	Common Name	S-(N-PhenethylthiocarbaMoyl)-L-cysteine
	CAS Number	53330-02-2	Molecular Weight	284.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₆N₂O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of S-(N-PhenethylthiocarbaMoyl)-L-cysteine

S-(N-PhenethylthiocarbaMoyl)-L-cysteine, a anticarcinogenic agent, has antileukaemic activity with a GC50 value of 336 nM. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells [1].

Name	phenethyl isothiocyanate cysteine conjugate
Synonym	More Synonyms

Description	S-(N-PhenethylthiocarbaMoyl)-L-cysteine, a anticarcinogenic agent, has antileukaemic activity with a GC50 value of 336 nM. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
In Vitro	S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits cell growth of HL60 cell, GC50=336 nM[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells, IC50=6.47μM[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine induced DNA fragmentation in HL 60 cells[1]. Cell Proliferation Assay[1] Cell Line: HL60 cells Concentration: 0.1-10 μM Incubation Time: 48 hours Result: Inhibited the cell growth with a GC50 value of 336 nM. Cell Proliferation Assay[1] Cell Line: HL60 cells Concentration: 4 μM Incubation Time: 0, 20, 40, 60, 80, 100 hours Result: Inhibited the cell growth.
References	[1]. [1] Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92.

Molecular Formula	C₁₂H₁₆N₂O₂S₂
Molecular Weight	284.40
Exact Mass	284.06500
PSA	132.74000
LogP	2.33990

Hazard Codes	Xi

Precursor 0
DownStream 2
CAS#:52-90-4 L-cysteine CAS#:2257-09-2 Phenylethyl iso...

s-(n-methylthiocarbamoyl)-l-cysteine

DC Chemicals Limited
China
Product Name: S-(N-PhenethylthiocarbaMoyl)-L-cysteine
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

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