BC-54
Modify Date: 2023-01-14 19:42:23
BC-54 structure
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Common Name | BC-54 | ||
|---|---|---|---|---|
| CAS Number | 534579-04-9 | Molecular Weight | 408.458 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BC-54A potent and biologically-active PDE4/7 inhibitor with IC50 of 50-100 nM for PDE4A/B/D, and 140 nM for both PDE7A/B; showed only modest activity (IC50=3 uM) against PDE2A and PDE11A, and little to no activity (IC50 >10 uM) against PDE1C/3B/5A /8A/9A/10A; displays exceptional anti-inflammatory activity and induces apoptosis in CLL cells. |
| Name | BC-54 |
|---|
| Description | A potent and biologically-active PDE4/7 inhibitor with IC50 of 50-100 nM for PDE4A/B/D, and 140 nM for both PDE7A/B; showed only modest activity (IC50=3 uM) against PDE2A and PDE11A, and little to no activity (IC50 >10 uM) against PDE1C/3B/5A /8A/9A/10A; displays exceptional anti-inflammatory activity and induces apoptosis in CLL cells. |
|---|---|
| References | References 1. de Medeiros AS, et al. Cell Signal. 2017 Sep 1;40:73-80. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C22H24N4O4 |
|---|---|
| Molecular Weight | 408.458 |