Dicyclohexylcarbodiimide

Modify Date: 2024-01-02 18:47:02

Dicyclohexylcarbodiimide Structure
Dicyclohexylcarbodiimide structure
Common Name Dicyclohexylcarbodiimide
CAS Number 538-75-0 Molecular Weight 206.33
Density 1.325 Boiling Point 122-124 ºC (6 torr)
Molecular Formula C13H22N2 Melting Point 34-35 °C(lit.)
MSDS Chinese USA Flash Point 87 ºC
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger

 Use of Dicyclohexylcarbodiimide


N,N-Dicyclohexylcarbodiimide(DCC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 1,3-dicyclohexylcarbodiimide
Synonym More Synonyms

 Dicyclohexylcarbodiimide Biological Activity

Description N,N-Dicyclohexylcarbodiimide(DCC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.325
Boiling Point 122-124 ºC (6 torr)
Melting Point 34-35 °C(lit.)
Molecular Formula C13H22N2
Molecular Weight 206.33
Flash Point 87 ºC
Exact Mass 206.178299
PSA 24.72000
LogP 5.54
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.567
Storage condition Store at RT.
Stability Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
Water Solubility Reaction

 MSDS

Name: Dicyclohexylcarbodi-imide Material Safety Data Sheet
Synonym: DCC; N,N'-Methanetetraylbiscyclohexanamine
CAS: 538-75-0
Section 1 - Chemical Product MSDS Name:Dicyclohexylcarbodi-imide Material Safety Data Sheet
Synonym:DCC; N,N'-Methanetetraylbiscyclohexanamine

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
538-75-0 Dicyclohexylcarbodiimide 100.0 208-704-1
Hazard Symbols: T
Risk Phrases: 22 24 41 43

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful if swallowed. Toxic in contact with skin. Risk of serious damage to eyes. May cause sensitization by skin contact.Moisture sensitive.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
Causes severe eye irritation.
Skin:
Causes moderate skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated.
Inhalation:
The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 538-75-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 122-124 deg C
Freezing/Melting Point: 34-35 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Reacts with water.
Specific Gravity/Density: Not available.
Molecular Formula: C13H22N2
Molecular Weight: 206.1674

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Acids, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 538-75-0: FF2160000 LD50/LC50:
CAS# 538-75-0: Dermal, guinea pig: LD50 = 10 mL/kg; Inhalation, rat: LC50 = 159 mg/m3/6H; Oral, mouse: LD50 = >800 mg/kg; Oral, rat: LD50 = 400 mg/kg.
Rat: LC50 = 0.159-0.417 Carcinogenicity:
Dicyclohexylcarbodiimide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 22 Harmful if swallowed.
R 24 Toxic in contact with skin.
R 41 Risk of serious damage to eyes.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
WGK (Water Danger/Protection)
CAS# 538-75-0: 2
Canada
CAS# 538-75-0 is listed on Canada's DSL List.
CAS# 538-75-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 538-75-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger
Hazard Statements H302 + H312-H315-H317-H318-H335-H336-H351-H373
Precautionary Statements P260-P280-P301 + P312 + P330-P305 + P351 + P338 + P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R21;R36/38;R41;R43
Safety Phrases S26-S36/37/39-S45-S41-S24-S37/39-S24/25-S36-S16-S53
RIDADR UN 2922 8/PG 2
WGK Germany 3
RTECS FF2160000
Packaging Group II
Hazard Class 6.1
HS Code 29252000

 Customs

HS Code 2921300090
Summary 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles186

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Pharm. Res. 32 , 2280-91, (2015)

A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cell...

 Synonyms

Cyclohexanamine, N-(cyclohexylcarbonimidoyl)-
N,N'-Methanetetraylbiscyclohexanamine
EINECS 208-704-1
N,N‘-Dicyclohexylcarbodimide
Methanediimine, N,N'-dicyclohexyl-
dicyclohexylcarbodiimide
dicyclohexyl-carbodiimide
Dicyclimide
1,3-di-cyclohexylcarbodiimide
N,N'-Dicyclohexylcarbodiimide
bis-cyclohexylcarbodiimide
Carbodicyclohexylimide
N,N'-Dicyclohexylcarbodimide
dcc solution
DCC
N,N′-Dicyclohexylcarbodiimide
Cyclohexanamine, N,N'-methanetetraylbis-
DCC/DCCI
Carbodiimide, dicyclohexyl-
N,N’-Dicyclohexylcarbodiimide (DCC)
MFCD00011659
N-(N-cyclohexylcarboximidoyl)cyclohexanamine
DCCI
N,N'-Methanediylidenedicyclohexanamine
N,N‘-Dicyclohexylcarbodiimide
1,3-dicyclohexylcarbodiimide
DCCD
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