(17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol

Modify Date: 2024-01-14 11:04:30

(17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol structure	Common Name	(17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol
	CAS Number	53866-33-4	Molecular Weight	274.394
	Density	1.2±0.1 g/cm3	Boiling Point	445.9±45.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₂₂D₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	209.6±23.3 °C

Use of (17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol

17β-Estradiol is the major estrogen secreted by the premenopausal ovary.

Name	(8R,9S,13S,14S,17S)-2,4-dideuterio-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	445.9±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₂D₂O₂
Molecular Weight	274.394
Flash Point	209.6±23.3 °C
Exact Mass	274.190186
PSA	40.46000
LogP	4.13
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.599

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG6814500

CHEMICAL NAME :: Estra-1,3,5(10)-triene-2,4-D2-3,17-diol, (17-beta)-

CAS REGISTRY NUMBER :: 53866-33-4

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H22-D2-O2

MOLECULAR WEIGHT :: 274.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 360 mg/kg/15W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: MOPMA3 Molecular Pharmacology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1965- Volume(issue)/page/year: 23,278,1983

Hazard Codes	T: Toxic;
Risk Phrases	R45

A-Estradiol-d2

Estra-1,3,5(10)-triene-2,4-d-3,17-diol, (17β)-

(17β)-(2,4-H)Estra-1,3,5(10)-triene-3,17-diol