sodium nicotinate

Modify Date: 2024-01-06 13:02:43

sodium nicotinate Structure
sodium nicotinate structure
Common Name sodium nicotinate
CAS Number 54-86-4 Molecular Weight 145.09100
Density 1.293g/cm3 Boiling Point 292.5ºC at 760mmHg
Molecular Formula C6H4NNaO2 Melting Point 236.6ºC
MSDS Chinese USA Flash Point 130.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name sodium,pyridine-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.293g/cm3
Boiling Point 292.5ºC at 760mmHg
Melting Point 236.6ºC
Molecular Formula C6H4NNaO2
Molecular Weight 145.09100
Flash Point 130.7ºC
Exact Mass 145.01400
PSA 53.02000

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QT2060000
CHEMICAL NAME :
Nicotinic acid, sodium salt
CAS REGISTRY NUMBER :
54-86-4
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H4-N-O2.Na
MOLECULAR WEIGHT :
145.10
WISWESSER LINE NOTATION :
T6NJ CVQ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 73,85,1941
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,95,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 81,1748,1961 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
30 mg/kg
SEX/DURATION :
female 9-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Effects on Newborn - behavioral
REFERENCE :
BRBUDU Brain Research Bulletin. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1976- Volume(issue)/page/year: 29,363,1992

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QT2060000
HS Code 2933399090

 Synthetic Route

~%

sodium nicotinate Structure

sodium nicotinate

CAS#:54-86-4

Literature: Journal of the Indian Chemical Society, , vol. 67, # 6 p. 463 - 465

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles49

More Articles
Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in mice.

Am. J. Physiol. Endocrinol. Metab. 307(7) , E563-70, (2014)

CL 316,243, a β3-adrenergic agonist, was developed as an antiobesity and diabetes drug and causes rapid decreases in blood glucose levels in mice. The mechanisms mediating this effect have not been fu...

The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.

J. Nutr. 143(7) , 1046-51, (2013)

In mammals, nicotinamide (Nam) is biosynthesized from l-tryptophan (l-Trp). The enzymes involved in the initial step of the l-Trp→Nam pathway are l-Trp-2,3-dioxygenase (TDO) and indoleamine-2,3-dioxyg...

Conversion of nicotinic acid to trigonelline is catalyzed by N-methyltransferase belonged to motif B' methyltransferase family in Coffea arabica.

Biochem. Biophys. Res. Commun. 452(4) , 1060-6, (2014)

Trigonelline (N-methylnicotinate), a member of the pyridine alkaloids, accumulates in coffee beans along with caffeine. The biosynthetic pathway of trigonelline is not fully elucidated. While it is qu...

 Synonyms

EINECS 200-215-1
NICOTINIC ACID,SODIUM SALT
3-pyridylcarboxylic acid sodium salt
3-Pyridinecarboxylic acid,sodium salt
pyridine-3-carboxylic acid sodium salt
sodium pyridine-3-carboxylate
Sodium nicotinate
MFCD00064352
Natriumnicotinat
Top Suppliers:I want be here



Get all suppliers and price by the below link:

sodium nicotinate suppliers

sodium nicotinate price