sodium nicotinate
sodium nicotinate structure
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Common Name | sodium nicotinate | ||
|---|---|---|---|---|
| CAS Number | 54-86-4 | Molecular Weight | 145.09100 | |
| Density | 1.293g/cm3 | Boiling Point | 292.5ºC at 760mmHg | |
| Molecular Formula | C6H4NNaO2 | Melting Point | 236.6ºC | |
| MSDS | Chinese USA | Flash Point | 130.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in mice.
Am. J. Physiol. Endocrinol. Metab. 307(7) , E563-70, (2014) CL 316,243, a β3-adrenergic agonist, was developed as an antiobesity and diabetes drug and causes rapid decreases in blood glucose levels in mice. The mechanisms mediating this effect have not been fully elucidated; thus, the purpose of the current study was ... |
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The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
J. Nutr. 143(7) , 1046-51, (2013) In mammals, nicotinamide (Nam) is biosynthesized from l-tryptophan (l-Trp). The enzymes involved in the initial step of the l-Trp→Nam pathway are l-Trp-2,3-dioxygenase (TDO) and indoleamine-2,3-dioxygenase (IDO). We aimed to determine whether tdo-knockout (td... |
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Conversion of nicotinic acid to trigonelline is catalyzed by N-methyltransferase belonged to motif B' methyltransferase family in Coffea arabica.
Biochem. Biophys. Res. Commun. 452(4) , 1060-6, (2014) Trigonelline (N-methylnicotinate), a member of the pyridine alkaloids, accumulates in coffee beans along with caffeine. The biosynthetic pathway of trigonelline is not fully elucidated. While it is quite likely that the production of trigonelline from nicotin... |
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Complementary feeding recommendations based on locally available foods in Indonesia.
Food Nutr. Bull. 35(4 Suppl) , S174-9, (2014) Affordable, locally contextual complementary feeding recommendations (CFRs) that take into account cultural diversity and differences in food availability will be more likely to result in long-term improvements in complementary feeding practices than general ... |
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Energy drinks and the unwanted buzz: a case report.
Md. Med. 13(4) , 28-9, (2013)
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Risk of hospitalized rhabdomyolysis associated with lipid-lowering drugs in a real-world clinical setting.
J. Clin. Lipidol. 7(2) , 102-8, (2013) The occurrence of low rates of rhabdomyolysis among patients receiving lipid-lowering drugs (LLDs) in randomized clinical trials may be elucidated with population-based studies.To determine the risk of hospitalized rhabdomyolysis associated with LLD therapy.T... |
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Gender differences in pharmacokinetics of a combination tablet of niacin extended-release/simvastatin in healthy Chinese volunteers.
Eur. J. Drug Metab. Pharmacokinet. 39(4) , 321-6, (2014) The gender differences in pharmacokinetics of a combination tablet of niacin extended-release/simvastatin were evaluated in healthy Chinese volunteers. Thirty-six healthy male and female volunteers were enrolled in the study receiving a single oral dose of ni... |
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Development of transgenic imazapyr-tolerant cowpea (Vigna unguiculata).
Plant Cell Rep. 32(4) , 537-43, (2013) Here we present the development of cowpea lines tolerant to a herbicide from imidazoline class (imazapyr). Plants presented tolerance to fourfold the commercial recommended dose for weed control. Cowpea is one of the most important and widely cultivated legum... |
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Nicotinic acid as a lipid-modifying drug--a review.
Atheroscler. Suppl. 14(1) , 7-13, (2013) Nicotinic acid has complex effects on lipoprotein metabolism; it increases HDL cholesterol, decreases triglycerides and LDL cholesterol. It also reduces lipoprotein(a) levels by about 25% and exerts certain effects that may be antiatherogenic. Studies perform... |
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Effectiveness of combination therapy with statin and another lipid-modifying agent compared with intensified statin monotherapy: a systematic review.
Ann. Intern. Med. 160(7) , 468-76, (2014) Some patients do not tolerate or respond to high-intensity statin monotherapy. Lower-intensity statin combined with nonstatin medication may be an alternative, but the benefits and risks compared with those of higher-intensity statin monotherapy are unclear.T... |