Albendazole Oxide

Modify Date: 2024-01-05 20:18:41

Albendazole Oxide Structure
Albendazole Oxide structure
Common Name Albendazole Oxide
CAS Number 54029-12-8 Molecular Weight 281.331
Density 1.4±0.1 g/cm3 Boiling Point 357.3ºC at 760 mmHg
Molecular Formula C12H15N3O3S Melting Point 154-156ºC
MSDS Chinese USA Flash Point 169.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Albendazole Oxide


Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

 Names

Name albendazole S-oxide
Synonym More Synonyms

 Albendazole Oxide Biological Activity

Description Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].
Related Catalog
References

[1]. Gokhan Adas,, et al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study).

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 357.3ºC at 760 mmHg
Melting Point 154-156ºC
Molecular Formula C12H15N3O3S
Molecular Weight 281.331
Flash Point 169.9ºC
Exact Mass 281.083405
PSA 103.29000
LogP 0.91
Index of Refraction 1.659
Storage condition -20°C Freezer

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
RIDADR NONH for all modes of transport
RTECS FD1080000

 Articles32

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Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism.

J. Anal. Toxicol. 39 , 374-86, (2015)

Opioid-related mortality rates have escalated. Drug interactions may increase blood concentrations of the opioid. We therefore used human liver microsomes (HLMs) and cDNA-expressed human cytochrome P4...

Validation of a streamlined multiclass, multiresidue method for determination of veterinary drug residues in bovine muscle by liquid chromatography-tandem mass spectrometry.

Anal. Bioanal. Chem 407 , 4423-35, (2015)

Multiclass, multiresidue methods are becoming increasingly popular in regulatory monitoring programs due to their increased analytical scope and laboratory efficiency. In this work, we report the deve...

The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum).

Vet. Parasitol. 176(1) , 27-33, (2011)

Albendazole (ABZ) is one of the most important benzimidazole compounds possessing high activity against the lancet fluke, Dicrocoelium dendriticum. ABZ sulphoxide (ABZ.SO) is the main molecule present...

 Synonyms

Rycobendazole
Carbamic acid, N-[5-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester
carbamic acid, N-[6-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester
MFCD00797922
Albendazole Sulfoxide
Albendazole S-oxide
Ricobendazole
Albendazole sulphoxide
Methyl [5-(propylsulfinyl)-1H-benzimidazol-2-yl]carbamate
Albendazole oxide
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