2,4-Dichloro-6-methylpyrimidine
2,4-Dichloro-6-methylpyrimidine structure
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Common Name | 2,4-Dichloro-6-methylpyrimidine | ||
|---|---|---|---|---|
| CAS Number | 5424-21-5 | Molecular Weight | 163.005 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 219.0±20.0 °C at 760 mmHg | |
| Molecular Formula | C5H4Cl2N2 | Melting Point | 44-47 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 107.0±7.4 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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4-Arylvinyl-2,6-di(pyridin-2-yl)pyrimidines: synthesis and optical properties.
J. Org. Chem. 76(10) , 3837-45, (2011) A series of 4-arylvinyl-2,6-di(pyridin-2-yl)pyrimidines have been efficiently prepared by a double cross-coupling reaction between 2,4-dichloro-6-methylpyrimidine and 2-(tributylstannyl)pyridine, followed by aldol condensation with the appropriate aromatic al... |
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Fluorous synthesis of disubstituted pyrimidines.
Org. Lett. 5(7) , 1011-3, (2003) [reaction: see text] The fluorous synthesis of disubstituted pyrimidines is carried out by attaching 2,4-dichloro-6-methylpyrimidine with 1H,1H,2H,2H-perfluorodecanethiol. The tagged substrate is substituted with 3-(trifluoromethyl)pyrazole followed by thioet... |
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Novel inhibitors of Rac1 in metastatic breast cancer.
P. R. Health Sci. J. 29(4) , 348-56, (2010) Rho family GTPases are molecular switches that control signaling pathways regulating a myriad of cellular functions. Rac1, a Rho family member, plays a critical role in several aspects of tumorigenesis, cancer progression, invasion, and metastasis. Rac protei... |