Gyrophoric acid
Modify Date: 2025-08-25 18:47:36
Gyrophoric acid structure
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Common Name | Gyrophoric acid | ||
|---|---|---|---|---|
| CAS Number | 548-89-0 | Molecular Weight | 468.410 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 693.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C24H20O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 238.5±25.0 °C | |
Use of Gyrophoric acidGyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2]. |
| Name | 4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Gyrophoric acid (200 μM) leads to significant decrease of mitochondrial membrane potential in ovarian cancer cells A2780 after 24 h long exposure but not in HT-29 colon adenocarcinoma cells. Gyrophoric acid significantly inhibits cell growth and affects the expression of Bcl-2, Bax and Hsp70 proteins but only on higher concentration in A375 melanoma cancer cells. Gyrophoric acid treatment on HeLa cells clearly indicates ROS production and apoptosis as form of occurred cell death. Moreover, DNA damage and changing activity of stress/survival proteins as p38MAPK, Erk1/2 and Akt mediated by Gyrophoric acid treatment confirm pro-apoptotic potential[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 693.9±55.0 °C at 760 mmHg |
| Molecular Formula | C24H20O10 |
| Molecular Weight | 468.410 |
| Flash Point | 238.5±25.0 °C |
| Exact Mass | 468.105652 |
| PSA | 170.82000 |
| LogP | 6.62 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.686 |
| InChIKey | ATQPZSQVWCPVGV-UHFFFAOYSA-N |
| SMILES | Cc1cc(OC(=O)c2c(C)cc(OC(=O)c3c(C)cc(O)cc3O)cc2O)cc(O)c1C(=O)O |
| Hazard Codes | Xi |
|---|
CAS#:480-64-8
CAS#:3187-58-4
CAS#:480-56-8
CAS#:504-15-4
CAS#:38862-71-4|
Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Effect on uncoupled photosystem 2 of spinach chloroplast assessed as inhibition of el...
Source: ChEMBL
Target: N/A
External Id: CHEMBL970895
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|
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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|
Name: Effect on uncoupled photosystem 2 of spinach leaves chloroplast assessed as inhibitio...
Source: ChEMBL
Target: N/A
External Id: CHEMBL970894
|
|
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
|
|
Name: Effect on uncoupled photosystem 2 of spinach chloroplast assessed as inhibition of el...
Source: ChEMBL
Target: N/A
External Id: CHEMBL970897
|
|
Name: Effect on uncoupled photosystem 2 of spinach chloroplast assessed as inhibition of el...
Source: ChEMBL
Target: N/A
External Id: CHEMBL970896
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|
Name: Effect on uncoupled photosystem 2 of spinach leaves chloroplast assessed as inhibitio...
Source: ChEMBL
Target: N/A
External Id: CHEMBL970891
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|
Name: Phytogrowth-inhibitory activity against Echinochloa crusgalli assessed as inhibition ...
Source: ChEMBL
Target: Echinochloa crus-galli
External Id: CHEMBL970890
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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| Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester |
| 4-({4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl}oxy)-2-hydroxy-6-methylbenzoic acid |
| Gyrophoric acid |
| Gyrophorsaeure |
| p-Triorsellinsaeure |
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