Daidzin

Modify Date: 2026-07-20 18:00:29

Daidzin structure	Common Name	Daidzin
	CAS Number	552-66-9	Molecular Weight	416.378
	Density	1.6±0.1 g/cm3	Boiling Point	727.6±60.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₀O₉	Melting Point	234-236°C
	MSDS	Chinese USA	Flash Point	259.8±26.4 °C

Use of Daidzin

Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	daidzein 7-O-β-D-glucoside
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism Natural Products >> Flavonoids Research Areas >> Others
References	[1]. Xie CI, et al. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. Alcohol Clin Exp Res. 1994 Dec;18(6):1443-7. [2]. Keung WM, et al. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry. 1998 Feb;47(4):499-506. [3]. Keung WM, et al. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1675-9.

Description

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism

Natural Products >> Flavonoids

Research Areas >> Others

References

[1]. Xie CI, et al. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. Alcohol Clin Exp Res. 1994 Dec;18(6):1443-7.

[2]. Keung WM, et al. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry. 1998 Feb;47(4):499-506.

[3]. Keung WM, et al. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1675-9.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.6±0.1 g/cm3
Boiling Point	727.6±60.0 °C at 760 mmHg
Melting Point	234-236°C
Molecular Formula	C₂₁H₂₀O₉
Molecular Weight	416.378
Flash Point	259.8±26.4 °C
Exact Mass	416.110718
PSA	149.82000
LogP	0.45
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.695
InChIKey	KYQZWONCHDNPDP-QNDFHXLGSA-N
SMILES	O=c1c(-c2ccc(O)cc2)coc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Daidzin MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ3094000

CHEMICAL NAME :: 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hy droxy-

CAS REGISTRY NUMBER :: 552-66-9

BEILSTEIN REFERENCE NO. :: 0059741

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H20-O9

MOLECULAR WEIGHT :: 416.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 13,51,1979

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DJ3094000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 7
CAS#:602329-60-2 4'-O-hexanoylda... CAS#:1105697-68-4 4'-O-hexanoylda... CAS#:486-66-8 Daidzein CAS#:602329-51-1 [4-(7-hydroxy-4...
CAS#:124590-31-4 Daidzin 6''-O-m... CAS#:17720-60-4 2,4-DIHYDROXYPH... CAS#:572-09-8 2,3,4,6-Tetra-O...
DownStream 3
CAS#:3682-01-7 Daidzein Diacetate CAS#:486-66-8 Daidzein CAS#:2280-44-6 D-glucopyranose

This table lists relevant public references with title, journal and publication metadata for this compound.

Comparing morphological, chemical and anti-diabetic characteristics of Puerariae Lobatae Radix and Puerariae Thomsonii Radix.

J. Ethnopharmacol. 164 , 53-63, (2015)

Puerariae Lobatae Radix (PLR) and Puerariae Thomsonii Radix (PTR) are traditional Chinese medicines used for the treatment of diabetes and cardiovascular diseases. These two herbs are used interchange...

A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia.

Fitoterapia 98 , 11-21, (2014)

The alpha7 nicotinic acetylcholine receptor (nAChR) is a potential target in neuroinflammation. Screening a plant extract library identified Solidago nemoralis as containing methyl-quercetin derivativ...

Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer.

Cancer Prev. Res. (Phila.) 8 , 1045-54, (2015)

Epidemiologic associations suggest that populations consuming substantial amounts of dietary soy exhibit a lower risk of prostate cancer. A 20-week randomized, phase II, crossover trial was conducted ...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr

Name: Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS-CoV-2-PP

Name: Inhibition of Saccharomyces cerevisiae alpha-glucosidase type 1 assessed as 4-nitroph...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3428155

Name: Antioxidant activity of the compound assessed as inhibition of ABTS radicals after 20...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3428156

Name: Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060535

Name: Inhibition of SARS coronavirus nsP13 helicase activity expressed in Escherichia coli ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060534

Name: Inhibition of cow milk xanthine oxidase at 50 ug/mL
Source: ChEMBL
Target: Xanthine dehydrogenase/oxidase
External Id: CHEMBL1015630

Name: Inhibition of HCV NS3 helicase ATP hydrolysis activity overexpressed in Escherichia c...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060537

Name: Inhibition of alpha glucosidase (unknown origin) using alpha PNPG as substrate preinc...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4015031

Name: Compound was evaluated for the inhibition of Hamster Liver mitochondrial Monoamine ox...
Source: ChEMBL
Target: Amine oxidase [flavin-containing] B
External Id: CHEMBL731144

Total 98, Current Page 1 of 10

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

daidzein 7-O-β-D-glucoside

Daidzein 7-O-glucoside

4'-hydroxyisoflavone-7-O-glucoside

Daidzin

Daidzein-7-glucoside

3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

4',7-hydroxyisoflavone-7-glucoside

MFCD00017466

3-(4-Hydroxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside

Daidzein-7-O-β-D-glucopyranoside

4',7-dihydroxyisoflavone-7-D-glucoside

7-O-B-D-GLUCOPYRANOSIDE

Diadzein 7-O-glucoside

Daidzoside

daidzein 7-O-beta-D-glucoside

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of daidzein 7-O-β-D-glucoside?

A: CAS number of daidzein 7-O-β-D-glucoside is 552-66-9.

Q: What are the uses of daidzein 7-O-β-D-glucoside?

A: Main uses of daidzein 7-O-β-D-glucoside: Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.

Q: What is the SMILES notation of daidzein 7-O-β-D-glucoside?

A: SMILES notation of daidzein 7-O-β-D-glucoside is O=c1c(-c2ccc(O)cc2)coc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12.

Q: What is the InChIKey of daidzein 7-O-β-D-glucoside?

A: InChIKey of daidzein 7-O-β-D-glucoside is KYQZWONCHDNPDP-QNDFHXLGSA-N.

Q: What are the upstream materials of daidzein 7-O-β-D-glucoside?

A: Related upstream materials(CAS) of daidzein 7-O-β-D-glucoside: 602329-60-2;1105697-68-4;486-66-8;602329-51-1;124590-31-4;17720-60-4;572-09-8.

Q: What is the molecular formula of daidzein 7-O-β-D-glucoside?

A: Molecular formula of daidzein 7-O-β-D-glucoside is C21H20O9.

Q: What are the downstream products of daidzein 7-O-β-D-glucoside?

A: Related downstream products(CAS) of daidzein 7-O-β-D-glucoside: 3682-01-7;486-66-8;2280-44-6.

Q: What is the polar surface area (PSA) of daidzein 7-O-β-D-glucoside?

A: Polar surface area (PSA) of daidzein 7-O-β-D-glucoside is 149.82000.

Q: What is the boiling point of daidzein 7-O-β-D-glucoside?

A: Boiling point of daidzein 7-O-β-D-glucoside is 727.6±60.0 °C at 760 mmHg.

Q: What is the English name of daidzein 7-O-β-D-glucoside?

A: The English name of daidzein 7-O-β-D-glucoside is daidzein 7-O-β-D-glucoside.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

BioBioPha

naturewill

Henan Tianfu Chemical Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Daidzin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: Daidzin
Price: ￥Inquiry/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

naturewill
China
Product Name: Daidzin
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Daidzin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Daidzin suppliers

Price: $55/10mM*1mLinDMSO

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Daidzin

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.