HISPIDIN

Modify Date: 2026-07-01 09:26:47

HISPIDIN Structure
HISPIDIN structure
Common Name HISPIDIN
CAS Number 555-55-5 Molecular Weight 246.21500
Density 1.657g/cm3 Boiling Point 554.2ºC at 760 mmHg
Molecular Formula C13H10O5 Melting Point 312-315ºC
MSDS Chinese USA Flash Point 220.1ºC

 Use of HISPIDIN


Hispidin, a PKC inhibitor and a phenolic compound from Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties[1].

 Names

Name hispidin
Synonym More Synonyms

 HISPIDIN Biological Activity

Description Hispidin, a PKC inhibitor and a phenolic compound from Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties[1].
Related Catalog
References

[1]. Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.

 Chemical & Physical Properties

Density 1.657g/cm3
Boiling Point 554.2ºC at 760 mmHg
Melting Point 312-315ºC
Molecular Formula C13H10O5
Molecular Weight 246.21500
Flash Point 220.1ºC
Exact Mass 246.05300
PSA 90.90000
LogP 1.92700
Index of Refraction 1.854
InChIKey SGJNQVTUYXCBKH-HNQUOIGGSA-N
SMILES O=c1cc(O)cc(C=Cc2ccc(O)c(O)c2)o1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles32

More Articles
Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-κB activation.

J. Sci. Food Agric. 95 , 2482-6, (2015)

Hispidin, a polyphenol compound mainly derived from the valuable medicinal mushroom Phellinus species, has been found to possess distinct biological effects. However, the anti-inflammatory potential o...

Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells.

Anticancer Res. 34(8) , 4087-93, (2014)

Few studies have been performed on the anticancer activity of hispidin, a phenolic compound produced from the medicinal mushroom Phellinus linteus. Herein, we studied hispidin-induced apoptosis, which...

The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.

Exp. Cell Res. 327(2) , 264-75, (2014)

Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardi...

 HISPIDINBioassay

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Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Cell Viability qHTS for small molecule stabilizers of the endoplasmic reticulum resid...
Source: NCGC
Target: N/A
External Id: SERCaMPGluc-f3-cellviability-42h
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Confirmatory qHTS for small molecule stabilizers of the endoplasmic reticulum residen...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-f1_f3-antagonist
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Counterscreen qHTS for small molecule stabilizers of the endoplasmic reticulum reside...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-f3-counterscreen-19h
Name: Antioxidant activity against Fe2+/ascorbic acid-induced lipid peroxidation in mouse l...
Source: ChEMBL
Target: Liver
External Id: CHEMBL2410971
Name: qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2...
Source: NCGC
Target: ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id: UBCH001
Name: Cytotoxicity against human HCT116 cells up to 200 uM by MTT assay
Source: ChEMBL
Target: HCT-116
External Id: CHEMBL2410970
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 Synonyms

6-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxypyran-2-one
6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
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