Polyphyllin VI

Modify Date: 2025-08-22 08:06:11

Polyphyllin VI Structure
Polyphyllin VI structure
Common Name Polyphyllin VI
CAS Number 55916-51-3 Molecular Weight 738.902
Density 1.4±0.1 g/cm3 Boiling Point 871.2±65.0 °C at 760 mmHg
Molecular Formula C39H62O13 Melting Point N/A
MSDS N/A Flash Point 480.7±34.3 °C

 Use of Polyphyllin VI


Polyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2].

 Names

Name polyphyllin D
Synonym More Synonyms

 Polyphyllin VI Biological Activity

Description Polyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2].
Related Catalog
References

[1]. Lin Z, et al. Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo. Phytother Res. 2015 Oct;29(10):1568-76.

[2]. Liu Y, et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5). pii: E201.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 871.2±65.0 °C at 760 mmHg
Molecular Formula C39H62O13
Molecular Weight 738.902
Flash Point 480.7±34.3 °C
Exact Mass 738.419067
PSA 196.99000
LogP 6.09
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.616
InChIKey WHWWQGPCTUQCMN-QEGKHCRGSA-N
SMILES CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1(O)C2C

 Synonyms

(3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
N1925
polyphyllin VI
β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-β-L-mannopyranosyl)-
(3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
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