(Pyr5)-Substance P (5-11)
Modify Date: 2024-01-08 18:21:28
(Pyr5)-Substance P (5-11) structure
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Common Name | (Pyr5)-Substance P (5-11) | ||
|---|---|---|---|---|
| CAS Number | 56104-22-4 | Molecular Weight | 852.011 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1374.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C41H57N9O9S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 785.3±34.3 °C | |
Use of (Pyr5)-Substance P (5-11)[Glp5] Substance P (5-11) is an octapeptide. [Glp5] Substance P (5-11) is one of the main substance P fragments in rat central nervous system (CNS). [Glp5] Substance P (5-11) locally modulates dopamine release in rat striatum[1]. |
| Name | N-[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanediamide |
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| Synonym | More Synonyms |
| Description | [Glp5] Substance P (5-11) is an octapeptide. [Glp5] Substance P (5-11) is one of the main substance P fragments in rat central nervous system (CNS). [Glp5] Substance P (5-11) locally modulates dopamine release in rat striatum[1]. |
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| Related Catalog | |
| In Vitro | [Glp5] Substance P (5-11) (0.12 nM-10 μM; rat striatum) modifies spontaneous dopamine outflow with a significant increase in dopamine outflow at 0.1 nM and a smaller effect at 1 nM, whereas concentrations lower than 0.1 nM or higher than 1 nM failed to modify dopamine release. [Glp5] Substance P (5-11) and K+ has additive effect, promoting the release of dopamine[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1374.9±65.0 °C at 760 mmHg |
| Molecular Formula | C41H57N9O9S |
| Molecular Weight | 852.011 |
| Flash Point | 785.3±34.3 °C |
| Exact Mass | 851.400024 |
| PSA | 315.18000 |
| LogP | 0.64 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.581 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Biological activity of C-terminal partial sequences of substance P.
J. Med. Chem. 19 , 854, (1976) Substance P (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) and the C-terminal partial sequences down to the tripeptide were synthesized by a solid-phase method. These peptides were assayed for vaso... |
| 5-Oxo-L-prolyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide |
| [pGlu5]-Substance P Fragment 5-11 |
| pGlu-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| L-Methioninamide, 5-oxo-L-prolyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl- |
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: (Pyr5)-Substance P (5-11)
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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