Hemopressin(rat)

Modify Date: 2024-01-10 10:23:19

Hemopressin(rat) Structure
Hemopressin(rat) structure
Common Name Hemopressin(rat)
CAS Number 568588-77-2 Molecular Weight 1088.26000
Density N/A Boiling Point N/A
Molecular Formula C53H77N13O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hemopressin(rat)


Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) exerts antinociceptive action in inflammatory pain models[1][2].

 Names

Name pvnfkflsh
Synonym More Synonyms

 Hemopressin(rat) Biological Activity

Description Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) exerts antinociceptive action in inflammatory pain models[1][2].
Related Catalog
In Vivo Hemopressin(rat) causes hypotension in anesthetized rats and is metabolized in vivo and in vitro by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE)[1]. Oral administration of Hemopressin(rat) inhibits mechanical hyperalgesia of CCI-rats up to 6h. Hemopressin(rat) treatment also decreases Egr-1 immunoreactivity (Egr-1Ir) in the superficial layer of the dorsal horn of the spinal cord of CCI rats[2].
References

[1]. Camila Squarzoni Dale, et al. Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin. em Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:105-6.

[2]. Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31.

 Chemical & Physical Properties

Molecular Formula C53H77N13O12
Molecular Weight 1088.26000
Exact Mass 1087.58000
PSA 400.15000
LogP 2.70800

 Synonyms

hemopressin
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