MK-2295

Modify Date: 2025-09-18 17:58:09

MK-2295 structure	Common Name	MK-2295
	CAS Number	573678-04-3	Molecular Weight	434.34
	Density	1.440±0.06 g/cm3(Predicted)	Boiling Point	500.9±50.0 °C(Predicted)
	Molecular Formula	C₂₁H₁₂F₆N₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MK-2295

MK-2295 (NGD-8243) is a TRPV1 antagonist. MK-2295 is an analgesic agent, and can be used for research of pain[1][2].

Name	N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine

Description	MK-2295 (NGD-8243) is a TRPV1 antagonist. MK-2295 is an analgesic agent, and can be used for research of pain[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Inflammation/Immunology
Target	TRPV1
References	[1]. Gunthorpe MJ, et al. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway. Drug Discov Today. 2009 Jan;14(1-2):56-67. [2]. Arthur Gomtsyan, et al. Chapter 8 - Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents. TRP Channels as Therapeutic Targets. From Basic Science to Clinical Use. 2015, Pages 129-144.

Density	1.440±0.06 g/cm3(Predicted)
Boiling Point	500.9±50.0 °C(Predicted)
Molecular Formula	C₂₁H₁₂F₆N₄
Molecular Weight	434.34

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NGD-8243
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Ngd-8243
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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