7-Methoxy-4-(trifluoromethyl)coumarin

Modify Date: 2024-01-03 13:16:03

7-Methoxy-4-(trifluoromethyl)coumarin Structure
7-Methoxy-4-(trifluoromethyl)coumarin structure
Common Name 7-Methoxy-4-(trifluoromethyl)coumarin
CAS Number 575-04-2 Molecular Weight 244.16700
Density 1.418g/cm3 Boiling Point 287.4ºC at 760 mmHg
Molecular Formula C11H7F3O3 Melting Point N/A
MSDS Chinese USA Flash Point 123.6ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 7-Methoxy-4-(trifluoromethyl)coumarin
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.418g/cm3
Boiling Point 287.4ºC at 760 mmHg
Molecular Formula C11H7F3O3
Molecular Weight 244.16700
Flash Point 123.6ºC
Exact Mass 244.03500
PSA 39.44000
LogP 2.82040
Index of Refraction 1.506

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
HS Code 2932209090

 Synthetic Route

~63%

7-Methoxy-4-(trifluoromethyl)coumarin Structure

7-Methoxy-4-(tr...

CAS#:575-04-2

Literature: Katkevics; Kontijevskis; Mutule; Suna Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 2 p. 151 - 159

~%

7-Methoxy-4-(trifluoromethyl)coumarin Structure

7-Methoxy-4-(tr...

CAS#:575-04-2

Literature: Journal of the Chemical Society, , p. 3235,3238

~%

7-Methoxy-4-(trifluoromethyl)coumarin Structure

7-Methoxy-4-(tr...

CAS#:575-04-2

Literature: Journal of the Chemical Society, , p. 3235,3238

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

More Articles
Identification and functional characterization of novel feline cytochrome P450 2A.

Xenobiotica 45 , 503-10, (2015)

1. Cytochrome P450s are the major metabolizing enzymes for xenobiotics in humans and other mammals. Although the domestic cat Felis catus, an obligate carnivore, is the most common companion animal, t...

Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity.

Expert Opin. Drug Metab. Toxicol. 10(10) , 1313-24, (2014)

Drug resistance by Plasmodium falciparum remains a challenge in malaria chemotherapy. This paper will focus on physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hy...

Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies.

Xenobiotica 44(7) , 615-26, (2014)

1. Cytochrome P450 enzyme system is the most important contributor to oxidative metabolism of drugs. Modification, and more specifically inhibition, of this system is an important determinant of sever...

 Synonyms

7-methoxy-4-(trifluoromethyl)chromen-2-one