CGP 7930

Modify Date: 2024-02-02 10:06:43

CGP 7930 structure	Common Name	CGP 7930
	CAS Number	57717-80-3	Molecular Weight	292.45600
	Density	0.971g/cm3	Boiling Point	364.7ºC at 760mmHg
	Molecular Formula	C₁₉H₃₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	152.6ºC

Use of CGP 7930

CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].

Name	3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethyl-1-propanol
Synonym	More Synonyms

Description	CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71.

Density	0.971g/cm3
Boiling Point	364.7ºC at 760mmHg
Molecular Formula	C₁₉H₃₂O₂
Molecular Weight	292.45600
Flash Point	152.6ºC
Exact Mass	292.24000
PSA	40.46000
LogP	4.54820