CGP 7930

Modify Date: 2025-08-27 07:34:36

CGP 7930 structure	Common Name	CGP 7930
	CAS Number	57717-80-3	Molecular Weight	292.45600
	Density	0.971g/cm3	Boiling Point	364.7ºC at 760mmHg
	Molecular Formula	C₁₉H₃₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	152.6ºC

Use of CGP 7930

CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].

Name	3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethyl-1-propanol
Synonym	More Synonyms

Description	CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71.

Density	0.971g/cm3
Boiling Point	364.7ºC at 760mmHg
Molecular Formula	C₁₉H₃₂O₂
Molecular Weight	292.45600
Flash Point	152.6ºC
Exact Mass	292.24000
PSA	40.46000
LogP	4.54820

WGK Germany	3

CGP 13501

CAS#:56189-68-5

~99%

CGP 7930

CAS#:57717-80-3

Literature: Kerr, David I. B.; Khalafy, Jabbar; Ong, Jennifer; Perkins, Michael V.; Prager, Rolf H.; Puspawati, Ni Made; Rimaz, Mehdi Australian Journal of Chemistry, 2006 , vol. 59, # 7 p. 457 - 462

2,6-Di-tert-but...

CAS#:128-39-2

CGP 7930

CAS#:57717-80-3

Literature: Kerr, David I. B.; Khalafy, Jabbar; Ong, Jennifer; Perkins, Michael V.; Prager, Rolf H.; Puspawati, Ni Made; Rimaz, Mehdi Australian Journal of Chemistry, 2006 , vol. 59, # 7 p. 457 - 462

Phenol,2,6-bis(...

CAS#:87-97-8

CGP 7930

CAS#:57717-80-3

Literature: Kerr, David I. B.; Khalafy, Jabbar; Ong, Jennifer; Perkins, Michael V.; Prager, Rolf H.; Puspawati, Ni Made; Rimaz, Mehdi Australian Journal of Chemistry, 2006 , vol. 59, # 7 p. 457 - 462

2,6-Di-tert-but...

CAS#:128-39-2

Neopentyl glycol

CAS#:126-30-7

4,4'-Ethylenebi...

CAS#:1516-94-5

CGP 7930

CAS#:57717-80-3

Literature: Krysin; Pustovskikh; Koptyug Russian Journal of General Chemistry, 2010 , vol. 80, # 10 p. 2001 - 2006

Precursor 4
CAS#:56189-68-5 CGP 13501 CAS#:128-39-2 2,6-Di-tert-but... CAS#:87-97-8 Phenol,2,6-bis(... CAS#:126-30-7 Neopentyl glycol
DownStream 0

cgp 7930

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CGP 7930

Use of CGP 7930

Names

CGP 7930 Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.