alpha-Tocopherol acetate

Modify Date: 2025-08-23 20:44:33

alpha-Tocopherol acetate Structure
alpha-Tocopherol acetate structure
Common Name alpha-Tocopherol acetate
CAS Number 58-95-7 Molecular Weight 472.743
Density 0.9±0.1 g/cm3 Boiling Point 184 ºC
Molecular Formula C31H52O3 Melting Point 28 ºC
MSDS Chinese USA Flash Point 235.6±24.7 °C

 Use of alpha-Tocopherol acetate


D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine[1].

 Names

Name D-alpha-Tocopheryl acetate
Synonym More Synonyms

 alpha-Tocopherol acetate Biological Activity

Description D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine[1].
Related Catalog
References

[1]. Fukui E, et al. Enhancing effect of medium-chain triglycerides on intestinal absorption of d-alpha-tocopherol acetate from lecithin-dispersed preparations in the rat. J Pharmacobiodyn. 1989 Feb;12(2):80-6.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 184 ºC
Melting Point 28 ºC
Molecular Formula C31H52O3
Molecular Weight 472.743
Flash Point 235.6±24.7 °C
Exact Mass 472.391632
PSA 35.53000
LogP 12.07
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.488
InChIKey ZAKOWWREFLAJOT-CEFNRUSXSA-N
SMILES CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(CCCC(C)CCCC(C)CCCC(C)C)O2
Water Solubility <0.1 g/100 mL at 17 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GP8280000
CHEMICAL NAME :
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
CAS REGISTRY NUMBER :
58-95-7
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C31-H52-O3
MOLECULAR WEIGHT :
472.83

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
182 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Blood - changes in other cell count (unspecified)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 24,1043,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80575 No. of Facilities: 149 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 8005 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80575 No. of Facilities: 834 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 8113 (estimated) No. of Female Employees: 5676 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS GP8280000

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 Synonyms

(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate
a-Tocopheryl Acetate
Vitamin E acetate
[2R*(4R*,8R*)]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol Acetate
EINECS 231-710-0
Eprolin
Tocopheryl acetate
E-Vimin
Evion
MFCD00072052
Vitamin- E acetate
D-α-Tocopheryl acetate
a-Tocopherol Acetate
TOCOPHEROL ACETATE
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