2-Aminoquinoline

Modify Date: 2024-01-02 14:06:38

2-Aminoquinoline structure	Common Name	2-Aminoquinoline
	CAS Number	580-22-3	Molecular Weight	144.17
	Density	1.2±0.1 g/cm3	Boiling Point	304.9±15.0 °C at 760 mmHg
	Molecular Formula	C₉H₈N₂	Melting Point	125 °C
	MSDS	Chinese USA	Flash Point	163.6±7.6 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of 2-Aminoquinoline

2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1].

Name	2-Aminoquinoline
Synonym	More Synonyms

Description	2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease
References	[1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165.

Density	1.2±0.1 g/cm3
Boiling Point	304.9±15.0 °C at 760 mmHg
Melting Point	125 °C
Molecular Formula	C₉H₈N₂
Molecular Weight	144.17
Flash Point	163.6±7.6 °C
Exact Mass	144.068741
PSA	38.91000
LogP	1.73
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.708
Water Solubility	soluble

2-Aminoquinoline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA9621800

CHEMICAL NAME :: Quinoline, 2-amino-

CAS REGISTRY NUMBER :: 580-22-3

BEILSTEIN REFERENCE NO. :: 0113163

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H8-N2

MOLECULAR WEIGHT :: 144.19

WISWESSER LINE NOTATION :: T66 BNJ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 500 nmol/plate

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 42,861,1978

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Hazard Codes	Xn: Harmful;
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S26-S36/37/39-S22
RIDADR	NONH for all modes of transport
RTECS	VA9621800
HS Code	2933499090

Precursor 8
CAS#:612-62-4 Chloroquinoline CAS#:2005-43-8 2-Bromoquinoline CAS#:113515-72-3 4-Chloro-8-ethy... CAS#:6560-83-4 Quinoline, 2-iodo-
CAS#:24255-31-0 benzyl-quinolin... CAS#:1613-37-2 quinoline 1-oxide CAS#:108-89-4 4-Picoline CAS#:74845-04-8 Z-1-cyano-2-(2'...
DownStream 8
CAS#:23862-56-8 ethyl N-quinoli... CAS#:580-21-2 2-FLUOROQUINOLINE CAS#:30958-68-0 2-Quinolinamine... CAS#:33757-48-1 N-quinolin-8-yl...
CAS#:74944-11-9 2-phenylimidazo... CAS#:94718-74-8 imidazo[1,2-a]q... CAS#:42485-44-9 3-(diethylamino... CAS#:50502-17-5 N-Quinolin-2-yl...

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synthesis and evaluation of the anti-nociceptive and anti-inflammatory activity of 4-aminoquinoline derivatives.

Bioorg. Med. Chem. 23 , 4390-6, (2015)

In this paper, we describe the synthesis and pharmacological evaluation of a series of 4-aminoquinolines. The compounds were characterised and tested in models of pain and inflammation, using the writ...

MFCD00038079

2(1H)-Quinolinimine

2-Aminoquindine

EINECS 209-458-8

2-Quinolinamine

iminoquinoline

quinolin-2-amine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Aminoquinoline
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Aminoquinoline
Price: ￥330.0/1g ￥1190.0/5g
Purity: 97.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Quinolin-2-amine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFUCHEM--High purity Quinolin-2-amine factory price
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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