N-nicotinoyl-Glycine
N-nicotinoyl-Glycine structure
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Common Name | N-nicotinoyl-Glycine | ||
|---|---|---|---|---|
| CAS Number | 583-08-4 | Molecular Weight | 180.161 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 512.5±30.0 °C at 760 mmHg | |
| Molecular Formula | C8H8N2O3 | Melting Point | 256-2580C (dec.) | |
| MSDS | Chinese USA | Flash Point | 263.7±24.6 °C | |
Use of N-nicotinoyl-GlycineNicotinuric acid is an acyl glycine. Nicotinuric acid is a metabolite of nicotinic acid. |
Summary: N-nicotinoylglycine (Chinese name: 烟酰甘氨酸), also known as N-nicotinoyl-Glycine, has a CAS number of 583-08-4. Its molecular formula is C8H8N2O3 and molecular weight is 180.161. It is a white solid with a melting point of 256-258°C (dec.) and a boiling point of 512.5±30.0 °C at 760 mmHg, with a density of 1.3±0.1 g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | N-nicotinoylglycine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Nicotinuric acid is an acyl glycine. Nicotinuric acid is a metabolite of nicotinic acid. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 512.5±30.0 °C at 760 mmHg |
| Melting Point | 256-2580C (dec.) |
| Molecular Formula | C8H8N2O3 |
| Molecular Weight | 180.161 |
| Flash Point | 263.7±24.6 °C |
| Exact Mass | 180.053497 |
| PSA | 79.29000 |
| LogP | -0.55 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.572 |
| InChIKey | ZBSGKPYXQINNGF-UHFFFAOYSA-N |
| SMILES | O=C(O)CNC(=O)c1cccnc1 |
| Storage condition | Store at 0-5°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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N-nicotinoyl-Glycine CAS#:583-08-4 |
| Literature: Archiv der Pharmazie (Weinheim, Germany), , vol. 284, p. 6 Journal of Biological Chemistry, , vol. 147, p. 651 |
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N-nicotinoyl-Glycine CAS#:583-08-4 |
| Literature: Biochemische Zeitschrift, , vol. 229, p. 154,156 Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <7> 3, p. 103,108 |
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~%
N-nicotinoyl-Glycine CAS#:583-08-4 |
| Literature: Biochemische Zeitschrift, , vol. 229, p. 154,156 Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <7> 3, p. 103,108 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 5 | |
CAS#:59-67-6
CAS#:124-38-9
CAS#:98-92-0
CAS#:144-62-7This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.
Kidney Int. 79(11) , 1244-53, (2011) Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used... |
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Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.
Biosci. Biotechnol. Biochem. 68(1) , 44-50, (2004) We investigated a useful chemical index for an excessive nicotinamide intake and how this excessive nicotinamide intake affects the tryptophan-nicotinamide metabolism in rats. Weaning rats were fed on... |
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Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
Int. J. Clin. Pharmacol. Ther. 45(8) , 448-54, (2007) To characterize plasma and urine pharmacokinetics of niacin and its metabolites after oral administration of 2,000 mg of extended-release (ER) niacin in healthy male volunteers.Niacin ER was administe... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Nicotinursaeure |
| N-Nicotinylglycine |
| N-(Pyridin-3-ylcarbonyl)glycine |
| Nicotinuric acid |
| N-(3-Pyridinylcarbonyl)glycine |
| Nicotinylglycine |
| Nicotinurate |
| [(3-pyridinylcarbonyl)amino]acetic acid |
| nicotinicamido acetic acid |
| Glycine,N-nicotinoyl |
| Nicotinoyl-Glycine |
| EINECS 209-497-0 |
| MFCD00023578 |
| N-(3-pyridinylcarbonyl)-glycine |
| N-nicotinoyl-Glycine |
| 2-(pyridine-3-carbonylamino)acetic acid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of N-nicotinoylglycine? |
| A: SMILES notation of N-nicotinoylglycine is O=C(O)CNC(=O)c1cccnc1. |
| Q: What is the polar surface area (PSA) of N-nicotinoylglycine? |
| A: Polar surface area (PSA) of N-nicotinoylglycine is 79.29000. |
| Q: What is the molecular weight of N-nicotinoylglycine? |
| A: Molecular weight of N-nicotinoylglycine is 180.161. |
| Q: What is the English name of N-nicotinoylglycine? |
| A: The English name of N-nicotinoylglycine is N-nicotinoylglycine. |
| Q: What is the melting point of N-nicotinoylglycine? |
| A: Melting point of N-nicotinoylglycine is 256-2580C (dec.). |
| Q: What are the storage conditions for N-nicotinoylglycine? |
| A: Storage conditions for N-nicotinoylglycine: Store at 0-5°C. |
| Q: What is the InChIKey of N-nicotinoylglycine? |
| A: InChIKey of N-nicotinoylglycine is ZBSGKPYXQINNGF-UHFFFAOYSA-N. |
| Q: What is the molecular formula of N-nicotinoylglycine? |
| A: Molecular formula of N-nicotinoylglycine is C8H8N2O3. |
| Q: What is the CAS number of N-nicotinoylglycine? |
| A: CAS number of N-nicotinoylglycine is 583-08-4. |
| Q: What are the downstream products of N-nicotinoylglycine? |
| A: Related downstream products(CAS) of N-nicotinoylglycine: 59-67-6;56-40-6;124-38-9;98-92-0;144-62-7. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |