Tagitinin F

Modify Date: 2024-02-24 20:25:21

Tagitinin F structure	Common Name	Tagitinin F
	CAS Number	59979-57-6	Molecular Weight	348.39
	Density	1.2±0.1 g/cm3	Boiling Point	512.9±50.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	181.1±23.6 °C

Use of Tagitinin F

Tagitinin F is a sesquiterpene with potent anti-inflammatory properities and nuclear factor-kappa B inhibition. Tagitinin F inhibits ipopolysaccharide-induced myeloperoxidase activity in human neutrophils. Tagitinin F decreases the secretion of inflammatory products without inducing apoptosis in neutrophils[1].

Name	Tagitinin F
Synonym	More Synonyms

Description	Tagitinin F is a sesquiterpene with potent anti-inflammatory properities and nuclear factor-kappa B inhibition. Tagitinin F inhibits ipopolysaccharide-induced myeloperoxidase activity in human neutrophils. Tagitinin F decreases the secretion of inflammatory products without inducing apoptosis in neutrophils[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Abe A E, et al. Anti-inflammatory sesquiterpene lactones from Tithonia diversifolia trigger different effects on human neutrophils[J]. Revista brasileira de farmacognosia, 2015, 25: 111-116.

Density	1.2±0.1 g/cm3
Boiling Point	512.9±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₄O₆
Molecular Weight	348.39
Flash Point	181.1±23.6 °C
Exact Mass	348.157288
PSA	82.06000
LogP	1.54
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.557

Hazard Codes	Xi

(4R,6R,7E,10Z)-...

CAS#:59979-56-5

~95%

Tagitinin F

CAS#:59979-57-6

Literature: Chowdhury, P. K.; Sharma, R. P.; Barua, J. N. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 4 p. 402

(5aR,8aR,9R,Z)-...

CAS#:72301-73-6

Tagitinin F

CAS#:59979-57-6

Literature: Chowdhury, P. K.; Sharma, R. P.; Baruah, J. N. Tetrahedron Letters, 1983 , vol. 24, # 48 p. 5429 - 5432

Precursor 2
CAS#:59979-56-5 (4R,6R,7E,10Z)-... CAS#:72301-73-6 (5aR,8aR,9R,Z)-...
DownStream 0

Propanoic acid, 2-methyl-, (3aR,4R,6S,9S,10Z,11aR)-2,3,3a,4,5,6,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester

tagitinin-F

Propanoic acid, 2-methyl-, (3aR,4R,6R,9R,10Z,11aR)-2,3,3a,4,5,6,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester

(1S,2Z,4R,8R,9R,11S)-1-Hydroxy-2,11-dimethyl-7-methylene-6-oxo-5,14-dioxatricyclo[9.2.1.0]tetradeca-2,12-dien-9-yl 2-methylpropanoate

(1R,2Z,4R,8R,9R,11R)-1-Hydroxy-2,11-dimethyl-7-methylene-6-oxo-5,14-dioxatricyclo[9.2.1.0]tetradeca-2,12-dien-9-yl 2-methylpropanoate