mercaptoethanol

Modify Date: 2026-07-02 07:08:48

mercaptoethanol Structure
mercaptoethanol structure
 Common Name mercaptoethanol
CAS Number 60-24-2 Molecular Weight 78.133
Density 1.1±0.1 g/cm3 Boiling Point 157.0±0.0 °C at 760 mmHg
Molecular Formula C2H6OS Melting Point -100 °C
MSDS Chinese USA Flash Point 73.9±0.0 °C
Symbol GHS05 GHS06 GHS08 GHS09
GHS05, GHS06, GHS08, GHS09		 Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name mercaptoethanol
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 157.0±0.0 °C at 760 mmHg
Melting Point -100 °C
Molecular Formula C2H6OS
Molecular Weight 78.133
Flash Point 73.9±0.0 °C
Exact Mass 78.013931
PSA 59.03000
LogP -0.23
Vapour density 2.69 (vs air)
Vapour Pressure 1.0±0.6 mmHg at 25°C
Index of Refraction 1.479
Water Solubility soluble
Freezing Point <100℃

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL5600000
CHEMICAL NAME :
Ethanol, 2-mercapto-
CAS REGISTRY NUMBER :
60-24-2
BEILSTEIN REFERENCE NO. :
0773648
LAST UPDATED :
199710
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C2-H6-O-S
MOLECULAR WEIGHT :
78.14
WISWESSER LINE NOTATION :
SH2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
244 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 ppm/8H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13200 mg/m3
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
150 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3220 mg/kg/4W-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :
Unscheduled DNA synthesis
TEST SYSTEM :
Rodent - mouse Cells - not otherwise specified
DOSE/DURATION :
30 mmol/L
REFERENCE :
BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 425,1,1976 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84674 No. of Facilities: 133 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 1437 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84674 No. of Facilities: 1497 (estimated) No. of Industries: 5 No. of Occupations: 13 No. of Employees: 14140 (estimated) No. of Female Employees: 4607 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS05 GHS06 GHS08 GHS09
GHS05, GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301 + H331-H310-H315-H317-H318-H373-H410
Precautionary Statements P261-P273-P280-P301 + P310-P302 + P350-P305 + P351 + P338
Target Organs Heart, Liver
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;
Risk Phrases R22;R24;R36/37/38;R51/53
Safety Phrases S26-S36/37/39-S45-S61-S29-S23
RIDADR UN 2966 6.1/PG 2
WGK Germany 3
RTECS KL5600000
Packaging Group II
Hazard Class 6.1
HS Code 2930909090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1516

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.

Biochem. J. 467(2) , 345-52, (2015)

Ubiquitylation regulates a multitude of biological processes and this versatility stems from the ability of ubiquitin (Ub) to form topologically different polymers of eight different linkage types. Wh...

Effect of (2)H and (18)O water isotopes in kinesin-1 gliding assay.

PeerJ 2 , e284, (2014)

We show for the first time the effects of heavy-hydrogen water ((2)H2O) and heavy-oxygen water (H2 (18)O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isot...

Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.

Mol. Pharm. 11(7) , 1991-6, (2014)

Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. H...

 mercaptoethanolBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of carbonic anhydrase 2 assessed as residual activity at 10 mM
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL929744
Name: Inhibition of metallo-beta-lactamase IMP-1 (unknown origin)
Source: ChEMBL
Target: N/A
External Id: CHEMBL3241404
Name: Inhibition of carbonic anhydrase 9 catalytic domain assessed as residual activity at ...
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL929745
Name: Inhibition of carbonic anhydrase 9 assessed as residual activity at 10 mM
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL929746
Name: Inhibition of carbonic anhydrase 9 assessed as residual activity at 1.0 mM
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL929740
Name: Inhibition of carbonic anhydrase 2 assessed as residual activity at 2.5 mM
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL929741
Name: Inhibition of carbonic anhydrase 9 catalytic domain assessed as residual activity at ...
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL929742
Name: Inhibition of carbonic anhydrase 9 assessed as residual activity at 2.5 mM
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL929743
Name: HIV Enzyme Data
Source: NIAID
Target: N/A
External Id: HIV Enzyme Data
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Total 26, Current Page 1 of 3
1
2
3

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

emery5791
2-ME
mercaptoethanol
2-hydroxyethane-1-thiol
mercaptoethyl alcohol
2-Sulfanylethanol
2-sulfhydryl-ethanol
Bis-Mercaptoethanol
usafek-4196
β-Hydroxyethylmercaptan
β-mercaptoethanol
β-Hydroxyethanethiol
BME
Monothioglycol
Sipomer 2ME
2-mercapto-1-ethanol
Monothioethylene glycol
2-hydroxyethyl mercaptan
2-hydroxyethanethiol
2-Mercaptoethanol
2-THIOETHANOL
EINECS 200-464-6
MFCD00004890
Monothioethyleneglycol
THIOGLYCOL
2-hydroxy ethanthiol

 mercaptoethanol | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of mercaptoethanol?
A: The English name of mercaptoethanol is mercaptoethanol.
Q: What is the molecular weight of mercaptoethanol?
A: Molecular weight of mercaptoethanol is 78.133.
Q: What are the upstream materials of mercaptoethanol?
A: Related upstream materials(CAS) of mercaptoethanol: 107-07-3;243671-61-6;1892-29-1;29167-28-0;81956-72-1;65-85-0;637-44-5;140-10-3;75-21-8.
Q: How is the water solubility of mercaptoethanol?
A: Water solubility of mercaptoethanol: soluble.
Q: What is the boiling point of mercaptoethanol?
A: Boiling point of mercaptoethanol is 157.0±0.0 °C at 760 mmHg.
Q: What are the downstream products of mercaptoethanol?
A: Related downstream products(CAS) of mercaptoethanol: 10603-78-8;10494-75-4;5271-38-5;52772-11-9;1226-99-9;3878-41-9;55764-23-3;147441-51-8;1462982-12-2;1462-55-1.
Q: What is the melting point of mercaptoethanol?
A: Melting point of mercaptoethanol is -100 °C.
Q: What is the safety information for mercaptoethanol?
A: Safety information for mercaptoethanol: S26-S36/37/39-S45-S61-S29-S23.
Q: What is the polar surface area (PSA) of mercaptoethanol?
A: Polar surface area (PSA) of mercaptoethanol is 59.03000.
Q: What is the CAS number of mercaptoethanol?
A: CAS number of mercaptoethanol is 60-24-2.

 mercaptoethanolfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
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Chemsrc provides mercaptoethanol(CAS#:60-24-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of mercaptoethanol are included as well.>> amp version: mercaptoethanol

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