Ald-Ph-NHS ester

Modify Date: 2024-01-02 20:44:38

Ald-Ph-NHS ester structure	Common Name	Ald-Ph-NHS ester
	CAS Number	60444-78-2	Molecular Weight	247.204
	Density	1.4±0.1 g/cm3	Boiling Point	425.4±47.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₉NO₅	Melting Point	163ºC
	MSDS	Chinese USA	Flash Point	211.1±29.3 °C

Use of Ald-Ph-NHS ester

Ald-Ph-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).

Name	N-Succinimidyl p-Formylbenzoate
Synonym	More Synonyms

Description	Ald-Ph-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
Related Catalog	Research Areas >> Cancer
Target	Noncleavable

Density	1.4±0.1 g/cm3
Boiling Point	425.4±47.0 °C at 760 mmHg
Melting Point	163ºC
Molecular Formula	C₁₂H₉NO₅
Molecular Weight	247.204
Flash Point	211.1±29.3 °C
Exact Mass	247.048065
PSA	80.75000
LogP	-0.20
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.606
Storage condition	-20°C

Ald-Ph-NHS ester MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
HS Code	2925190090

N-Hydroxysuccinimide

CAS#:6066-82-6

4-Formylbenzoic acid

CAS#:619-66-9

~99%

Ald-Ph-NHS ester

CAS#:60444-78-2

Literature: Quinton, Julia; Kolodych, Sergii; Chaumonet, Manon; Bevilacqua, Valentina; Nevers, Marie-Claire; Volland, Herve; Gabillet, Sandra; Thuery, Pierre; Creminon, Christophe; Taran, Frederic Angewandte Chemie - International Edition, 2012 , vol. 51, # 25 p. 6144 - 6148

TSTU

CAS#:105832-38-0

4-Formylbenzoic acid

CAS#:619-66-9

Ald-Ph-NHS ester

CAS#:60444-78-2

Literature: Organic and Biomolecular Chemistry, , vol. 8, # 19 p. 4329 - 4345

Precursor 3
CAS#:6066-82-6 N-Hydroxysuccinimide CAS#:619-66-9 4-Formylbenzoic acid CAS#:105832-38-0 TSTU
DownStream 0

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer.

Biomaterials 80 , 57-67, (2016)

Metastatic prostate cancer causes significant morbidity and mortality and there is a critical unmet need for effective treatments. We have developed a theranostic nanoplex platform for combined imagin...

A strategy for the systematic development of a liquid chromatographic mass spectrometric screening method for polymer electrolyte membrane degradation products using isocratic and gradient phase optimized liquid chromatography.

J. Chromatogr. A. 1216 , 8910-8917, (2009)

Within the scope of research for target and non-target LC-MS/MS analysis of membrane degradation products of polymer electrolyte membrane fuel cells, a systematic method development for the separation...

Synthesis of pH-sensitive amphotericin B-poly(ethylene glycol) conjugates and study of their controlled release in vitro.

Bioorg. Med. Chem. 15 , 4069-4076, (2007)

New intravenous conjugates of amphotericin B (AMB) with poly(ethylene glycols) (PEG) (M=5000, 10,000, 20,000) have been synthesized and characterised. The intermediate PEGs possess a 1,4-disubstituted...

Benzaldehyde, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-

(2,5-dioxopyrrolidin-1-yl) 4-formylbenzoate

4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}benzaldehyde