(+)-Nortrachelogenin

Modify Date: 2024-01-01 19:46:59

(+)-Nortrachelogenin Structure
(+)-Nortrachelogenin structure
Common Name (+)-Nortrachelogenin
CAS Number 61521-74-2 Molecular Weight 374.384
Density 1.4±0.1 g/cm3 Boiling Point 609.2±50.0 °C at 760 mmHg
Molecular Formula C20H22O7 Melting Point N/A
MSDS N/A Flash Point 217.3±23.6 °C

 Use of (+)-Nortrachelogenin


(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity[1].

 Names

Name (3R,4R)-3-hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
Synonym More Synonyms

 (+)-Nortrachelogenin Biological Activity

Description (+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity[1].
Related Catalog
In Vitro Wikstromol induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway[2].
References

[1]. A Kato,et al. (+)-Nortrachelogenin, A New Pharmacologically Active Lignan From Wikstroemia indica. J Nat Prod. 1979 Mar;42(2):159-162.

[2]. Huankai Yao, et al. Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 609.2±50.0 °C at 760 mmHg
Molecular Formula C20H22O7
Molecular Weight 374.384
Flash Point 217.3±23.6 °C
Exact Mass 374.136566
PSA 105.45000
LogP 0.92
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.630

 Safety Information

Hazard Codes Xi
HS Code 2932209090

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(3R,4R)-3-Hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydro-2(3H)-furanone
2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-
(3R-cis)-Dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-3-hydroxy-2(3H)-furanone
2(3H)-Furanone, dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-3-hydroxy-, (3R-cis)-
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