(+)-Nortrachelogenin

Modify Date: 2025-08-23 10:09:40

(+)-Nortrachelogenin structure	Common Name	(+)-Nortrachelogenin
	CAS Number	61521-74-2	Molecular Weight	374.384
	Density	1.4±0.1 g/cm3	Boiling Point	609.2±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	217.3±23.6 °C

Use of (+)-Nortrachelogenin

(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity[1].

Name	(3R,4R)-3-hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
Synonym	More Synonyms

Description	(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
In Vitro	Wikstromol induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway[2].
References	[1]. A Kato,et al. (+)-Nortrachelogenin, A New Pharmacologically Active Lignan From Wikstroemia indica. J Nat Prod. 1979 Mar;42(2):159-162. [2]. Huankai Yao, et al. Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.

Density	1.4±0.1 g/cm3
Boiling Point	609.2±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₇
Molecular Weight	374.384
Flash Point	217.3±23.6 °C
Exact Mass	374.136566
PSA	105.45000
LogP	0.92
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.630
InChIKey	ZITBJWXLODLDRH-JLTOFOAXSA-N
SMILES	COc1cc(CC2COC(=O)C2(O)Cc2ccc(O)c(OC)c2)ccc1O

Hazard Codes	Xi
HS Code	2932209090

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(3R,4R)-3-Hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydro-2(3H)-furanone

2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-

(3R-cis)-Dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-3-hydroxy-2(3H)-furanone

2(3H)-Furanone, dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-3-hydroxy-, (3R-cis)-

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