Helichrysetin

Modify Date: 2024-01-10 15:26:15

Helichrysetin Structure
Helichrysetin structure
Common Name Helichrysetin
CAS Number 62014-87-3 Molecular Weight 286.279
Density 1.4±0.1 g/cm3 Boiling Point 532.0±50.0 °C at 760 mmHg
Molecular Formula C16H14O5 Melting Point N/A
MSDS N/A Flash Point 201.0±23.6 °C

 Use of Helichrysetin


Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2].

 Names

Name (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-prop en-1-one
Synonym More Synonyms

 Helichrysetin Biological Activity

Description Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2].
Related Catalog
References

[1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90.

[2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 532.0±50.0 °C at 760 mmHg
Molecular Formula C16H14O5
Molecular Weight 286.279
Flash Point 201.0±23.6 °C
Exact Mass 286.084137
PSA 86.99000
LogP 3.08
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.684

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

Helichrysetin
4',6'-dihydroxy-2',4-dimethoxychalcone
2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-
(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
6'-O-methylisosalipurpol