2-(Benzyloxy)ethanol

Q: What is the safety information for 2-Benzyloxyethanol?

Safety information for 2-Benzyloxyethanol: S26-S36-S37/39.

Q: What is the boiling point of 2-Benzyloxyethanol?

Boiling point of 2-Benzyloxyethanol is 254.4±15.0 °C at 760 mmHg.

Q: What is the LogP of 2-Benzyloxyethanol?

LogP of 2-Benzyloxyethanol is 1.38.

Q: What is the SMILES notation of 2-Benzyloxyethanol?

SMILES notation of 2-Benzyloxyethanol is OCCOCc1ccccc1.

Q: What is the melting point of 2-Benzyloxyethanol?

Melting point of 2-Benzyloxyethanol is <-75ºC.

Q: What are the upstream materials of 2-Benzyloxyethanol?

Related upstream materials(CAS) of 2-Benzyloxyethanol: 100-39-0;107-21-1;100-44-7;936-51-6;60656-87-3;31600-43-8;96-49-1;106-44-5;122-99-6.

Q: What English synonyms does 2-Benzyloxyethanol have?

English synonyms of 2-Benzyloxyethanol: 2-(Benzyloxy)ethanol, 2-(Benzyl-Oxy)Ethan-1-Ol, MFCD00002868, 2-phenylmethoxyethanol, Benzyl cellosolve, Glycol benzyl ether, UNII-06S8147L47, EINECS 210-719-3, ethylene glycol monobenzyl ether.

Q: What is the CAS number of 2-Benzyloxyethanol?

CAS number of 2-Benzyloxyethanol is 622-08-2.

Q: What is the molecular formula of 2-Benzyloxyethanol?

Molecular formula of 2-Benzyloxyethanol is C9H12O2.

Q: What is the English name of 2-Benzyloxyethanol?

The English name of 2-Benzyloxyethanol is 2-Benzyloxyethanol.

Modify Date: 2026-06-30 16:48:52

2-(Benzyloxy)ethanol structure	Common Name	2-(Benzyloxy)ethanol
	CAS Number	622-08-2	Molecular Weight	152.190
	Density	1.1±0.1 g/cm3	Boiling Point	254.4±15.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₂O₂	Melting Point	<-75ºC
	MSDS	Chinese USA	Flash Point	108.0±14.6 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2-(Benzyloxy)ethanol

2-(Benzyloxy)ethanol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	2-Benzyloxyethanol
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	2-(Benzyloxy)ethanol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Reed NN, et al. A one-step synthesis of monoprotected polyethylene glycol ethers. J Org Chem. 2000 Sep 8;65(18):5843-5.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	254.4±15.0 °C at 760 mmHg
Melting Point	<-75ºC
Molecular Formula	C₉H₁₂O₂
Molecular Weight	152.190
Flash Point	108.0±14.6 °C
Exact Mass	152.083725
PSA	29.46000
LogP	1.38
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.525
InChIKey	CUZKCNWZBXLAJX-UHFFFAOYSA-N
SMILES	OCCOCc1ccccc1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

2-(Benzyloxy)ethanol MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KJ7550000

CHEMICAL NAME :: Ethanol, 2-(benzyloxy)-

CAS REGISTRY NUMBER :: 622-08-2

BEILSTEIN REFERENCE NO. :: 2043566

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H12-O2

MOLECULAR WEIGHT :: 152.21

WISWESSER LINE NOTATION :: Q2O1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1190 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	KJ7550000
HS Code	2909499000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:100-39-0 Benzyl bromide CAS#:107-21-1 Ethylene glycol CAS#:100-44-7 Benzyl chloride CAS#:936-51-6 2-phenyl-1,3-di...
CAS#:60656-87-3 2-(Benzyloxy)ac... CAS#:31600-43-8 Methyl 2-(benzy... CAS#:96-49-1 Ethylene carbonate CAS#:106-44-5 p-Cresol
CAS#:122-99-6 Phenoxyethanol
DownStream 10
CAS#:38336-04-8 2-benzyloxyethy... CAS#:420137-14-0 3-Benzyloxypyrr... CAS#:936-51-6 2-phenyl-1,3-di... CAS#:23043-24-5 p-Toluidine, al...
CAS#:2050-25-1 Diethylene Glyc... CAS#:107-21-1 Ethylene glycol CAS#:82166-21-0 2-methyl cyclohexane CAS#:1462-37-9 Benzyl 2-Bromoe...
CAS#:100-39-0 Benzyl bromide CAS#:86259-87-2 Tetraethylene G...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Alkylation of active methylene compounds with alcohols catalyzed by an iridium complex.

Chem. Commun. (Camb.) , 2850, (2007)

Base-free catalytic alpha-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)](2) complex in the presence of PPh(3) to afford the corresponding...

A structure-based library approach to kinase inhibitors. Norman TC, et al.

J. Am. Chem. Soc. 118(31) , 7430-31, (1996)

Poly (benzyloxy ethyl methacrylate): preparation by free radical polymerization and by group transfer polymerization; with subsequent debenzylation to form poly (2-hydroxyethyl methacrylate). Dyakonov TA, et al.

Eur. Polymer J. 36(9) , 1779-93, (2000)

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-(Benzyloxy)ethanol

2-(Benzyl-Oxy)Ethan-1-Ol

MFCD00002868

2-phenylmethoxyethanol

Benzyl cellosolve

Glycol benzyl ether

UNII-06S8147L47

EINECS 210-719-3

ethylene glycol monobenzyl ether

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the safety information for 2-Benzyloxyethanol?

A: Safety information for 2-Benzyloxyethanol: S26-S36-S37/39.

Q: What is the boiling point of 2-Benzyloxyethanol?

A: Boiling point of 2-Benzyloxyethanol is 254.4±15.0 °C at 760 mmHg.

Q: What is the LogP of 2-Benzyloxyethanol?

A: LogP of 2-Benzyloxyethanol is 1.38.

Q: What is the SMILES notation of 2-Benzyloxyethanol?

A: SMILES notation of 2-Benzyloxyethanol is OCCOCc1ccccc1.

Q: What is the melting point of 2-Benzyloxyethanol?

A: Melting point of 2-Benzyloxyethanol is <-75ºC.

Q: What are the upstream materials of 2-Benzyloxyethanol?

A: Related upstream materials(CAS) of 2-Benzyloxyethanol: 100-39-0;107-21-1;100-44-7;936-51-6;60656-87-3;31600-43-8;96-49-1;106-44-5;122-99-6.

Q: What English synonyms does 2-Benzyloxyethanol have?

A: English synonyms of 2-Benzyloxyethanol: 2-(Benzyloxy)ethanol, 2-(Benzyl-Oxy)Ethan-1-Ol, MFCD00002868, 2-phenylmethoxyethanol, Benzyl cellosolve, Glycol benzyl ether, UNII-06S8147L47, EINECS 210-719-3, ethylene glycol monobenzyl ether.

Q: What is the CAS number of 2-Benzyloxyethanol?

A: CAS number of 2-Benzyloxyethanol is 622-08-2.

Q: What is the molecular formula of 2-Benzyloxyethanol?

A: Molecular formula of 2-Benzyloxyethanol is C9H12O2.

Q: What is the English name of 2-Benzyloxyethanol?

A: The English name of 2-Benzyloxyethanol is 2-Benzyloxyethanol.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-(Benzyloxy)ethanol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(Benzyloxy)ethanol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 2-(Benzyloxy)ethanol
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Price: ￥550/100 mg

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2-(Benzyloxy)ethanol

Use of 2-(Benzyloxy)ethanol

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