PIP-199

Modify Date: 2024-01-23 14:42:37

PIP-199 Structure
PIP-199 structure
Common Name PIP-199
CAS Number 622795-76-0 Molecular Weight 456.54
Density N/A Boiling Point N/A
Molecular Formula C27H28N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PIP-199


PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM). PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.

 Names

Name PIP-199
Synonym More Synonyms

 PIP-199 Biological Activity

Description PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM). PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.

 Chemical & Physical Properties

Molecular Formula C27H28N4O3
Molecular Weight 456.54
Storage condition -20°C

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD04443596