ICI 199,441 hydrochloride

Modify Date: 2025-08-26 21:43:57

ICI 199,441 hydrochloride Structure
ICI 199,441 hydrochloride structure
 Common Name ICI 199,441 hydrochloride
CAS Number 115199-84-3 Molecular Weight 427.80
Density N/A Boiling Point 532.8ºC at 760mmHg
Molecular Formula C21H25Cl3N2O Melting Point N/A
MSDS N/A Flash Point 276ºC

 Use of ICI 199,441 hydrochloride


ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion[1].

 Names

Name ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
Synonym More Synonyms

 ICI 199,441 hydrochloride Biological Activity

Description ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion[1].
Related Catalog
In Vivo ICI 199441 (Wistar rats, 0.1 mg/kg, IV, once) administered 15 min before ischemia produces a potent antiarrhythmic effect[1].
References

[1]. Tsibulnikov SY, et al. Prospects of Using of κ-Opioid Receptor Agonists U-50,488 and ICI 199,441 for Improving Heart Resistance to Ischemia/Reperfusion. Bull Exp Biol Med. 2015;159(6):718-721.

 Chemical & Physical Properties

Boiling Point 532.8ºC at 760mmHg
Molecular Formula C21H25Cl3N2O
Molecular Weight 427.80
Flash Point 276ºC
Exact Mass 426.10300
PSA 23.55000
LogP 5.57130
Vapour Pressure 1.97E-11mmHg at 25°C

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

ici 199,441
ici 199,441 hydrochloride
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Chemsrc provides ICI 199,441 hydrochloride(CAS#:115199-84-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ICI 199,441 hydrochloride are included as well.>> amp version: ICI 199,441 hydrochloride

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