Pip-alkyne-Ph-COOCH3

Modify Date: 2024-01-14 07:53:58

Pip-alkyne-Ph-COOCH3 Structure
Pip-alkyne-Ph-COOCH3 structure
Common Name Pip-alkyne-Ph-COOCH3
CAS Number 2308496-47-9 Molecular Weight 243.30
Density N/A Boiling Point N/A
Molecular Formula C15H17NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pip-alkyne-Ph-COOCH3


Pip-alkyne-Ph-COOCH3 is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC ARD-266[1].

 Names

Name Pip-alkyne-Ph-COOCH3

 Pip-alkyne-Ph-COOCH3 Biological Activity

Description Pip-alkyne-Ph-COOCH3 is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC ARD-266[1].
Related Catalog
Target

Alkyl-Chain

In Vitro ARD-266 is a a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader[1].
References

[1]. Han X, et al. Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands. J Med Chem. 2019 Dec 26;62(24):11218-11231.

 Chemical & Physical Properties

Molecular Formula C15H17NO2
Molecular Weight 243.30

 Safety Information

Hazard Codes Xi