Kuwanon A

Modify Date: 2024-01-09 18:57:44

Kuwanon A Structure
Kuwanon A structure
Common Name Kuwanon A
CAS Number 62949-77-3 Molecular Weight 420.45400
Density N/A Boiling Point N/A
Molecular Formula C25H24O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Kuwanon A


Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.

 Names

Name Kuwanon A
Synonym More Synonyms

 Kuwanon A Biological Activity

Description Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
Related Catalog
Target

IC50: 10.5 μM (nitric oxide)[1]

In Vitro Kuwanon A shows significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes with TG inhibition values of 47.1%. Kuwanon A also shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells with an IC50 of 10.5 μM[1].
Cell Assay RAW264.7 cells are treated with Kuwanon A (3, 10, 20, 30, 100 μM). Cell viability is measured using the MTT assay[1].
References

[1]. Yang ZG, et al. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16(7):6010-22.

 Chemical & Physical Properties

Molecular Formula C25H24O6
Molecular Weight 420.45400
Exact Mass 420.15700
PSA 100.13000
LogP 5.26970
Storage condition 2-8℃

 Synonyms

kuwanon A
5,7,5'-trihydroxy-2',2'-dimethyl-3-(3-methyl-but-2-enyl)-2'H-[2,8']bichromenyl-4-one
Kuwanon
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