Colfosceril palmitate

Colfosceril palmitate Structure
Colfosceril palmitate structure
Common Name Colfosceril palmitate
CAS Number 63-89-8 Molecular Weight 734.039
Density N/A Boiling Point N/A
Molecular Formula C40H80NO8P Melting Point 229-229.5 °C
MSDS Chinese USA Flash Point N/A

Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.

Int. J. Pharm. 473(1-2) , 334-44, (2014)

CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the neuroprotective effect of NGF. CRM197/CL-liposoms were incuba...

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Si...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite ref...

Relationship between peptide structure and antimicrobial activity as studied by de novo designed peptides.

Biochim. Biophys. Acta 1838(12) , 2985-93, (2014)

As fundamental components in innate immunity, antimicrobial peptides (AMPs) hold great potentials in the treatment of persistent infections involving slow-growing or dormant bacteria in which, selective inhibition of prokaryotic bacteria in the context of euk...

Effects of fatty acyl chain length, double-bond number and matrix on phosphatidylcholine responses in matrix-assisted laser desorption/ionization on an Orbitrap mass spectrometer.

Rapid Commun. Mass Spectrom. 29 , 2374-84, (2015)

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is used for the fast qualitative and quantitative analysis of phosphatidylcholines (PC). Fatty acyl chain lengths and the number of double bonds (DB) affect relative responses of PC; hen...

Defective functionality of HDL particles in familial apoA-I deficiency: relevance of alterations in HDL lipidome and proteome.

J. Lipid Res. 55(12) , 2509-20, (2014)

To evaluate functional and compositional properties of HDL in subjects from a kindred of genetic apoA-I deficiency, two homozygotes and six heterozygotes, with a nonsense mutation at APOA1 codon -2, Q[-2]X, were recruited together with age- and sex-matched he...

Phase coexistence in films composed of DLPC and DPPC: A comparison between different model membrane systems

Biochim. Biophys. Acta 1838(7) , 1823-31, (2014)

For the biophysical study of membranes, a variety of model systems have been used to measure the different parameters and to extract general principles concerning processes that may occur in cellular membranes. However, there are very few reports in which the...

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction.

ACS Nano 9 , 9912-21, (2015)

The functionalized lipid shell of hybrid nanoparticles plays an important role for improving their biocompatibility and in vivo stability. Yet few efforts have been made to critically examine the shell structure of nanoparticles and its effect on cell-particl...

Unusual penetration of phospholipid mono- and bilayers byQuillajabark saponin biosurfactant

Biochim. Biophys. Acta 1838(7) , 1931-40, (2014)

The interactions between a model phospholipid 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a biosurfactant Quillaja Bark Saponin (QBS) obtained from the bark of Quillaja saponaria Molina were studied using simple models of biological membranes. QBS ...

Localized delivery of doxorubicin in vivo from polymer-modified thermosensitive liposomes with MR-guided focused ultrasound-mediated heating.

J. Control. Release 194 , 71-81, (2014)

Thermosensitive liposomes have emerged as a viable strategy for localized delivery and triggered release of chemotherapy. MR-guided focused ultrasound (MRgFUS) has the capability of heating tumors in a controlled manner, and when combined with thermosensitive...