BULBOCAPNINE HYDROCHLORIDE

Modify Date: 2025-08-20 18:03:32

BULBOCAPNINE HYDROCHLORIDE Structure
BULBOCAPNINE HYDROCHLORIDE structure
Common Name BULBOCAPNINE HYDROCHLORIDE
CAS Number 632-47-3 Molecular Weight 361.82
Density N/A Boiling Point 504ºC at 760 mmHg
Molecular Formula C19H20ClNO4 Melting Point 209-210ºC
MSDS USA Flash Point 258.6ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of BULBOCAPNINE HYDROCHLORIDE


Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor. Bulbocapnine hydrochloride inhibits dopamine synthesis. Bulbocapnine hydrochloride also has neuroleptic-like, anticonvulsant and antinociceptive effects[1][2][3].

 Names

Name bulbocapnine hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 504ºC at 760 mmHg
Melting Point 209-210ºC
Molecular Formula C19H20ClNO4
Molecular Weight 361.82
Flash Point 258.6ºC
Exact Mass 361.10800
PSA 51.16000
LogP 3.62150
Appearance of Characters solid | tan
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CE1054000
CHEMICAL NAME :
6a-alpha-Aporphin-11-ol, 10-methoxy-1,2-(methylenedioxy)-, hydrochloride
CAS REGISTRY NUMBER :
632-47-3
LAST UPDATED :
199012
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H19-N-O4.Cl-H
MOLECULAR WEIGHT :
361.85
WISWESSER LINE NOTATION :
T D56 J666 1A T EO GO RN FH&&&TTJ KQ LO1 R1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
55 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 236,149,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 31,27,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 137,375,1962

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
Safety Phrases 36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS CE1054000

 Synonyms

N-METHYLLAUNOBINE HYDROCHLORIDE
MFCD00069363
EINECS 211-178-6
BULBOCAPNINE HCL
Buibocapnine hydrochloride
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