Aivlosin

Modify Date: 2024-01-03 08:46:06

Aivlosin structure	Common Name	Aivlosin
	CAS Number	63409-12-1	Molecular Weight	1042.25
	Density	1.21g/cm3	Boiling Point	1005.4ºC at 760 mmHg
	Molecular Formula	C₅₃H₈₇NO₁₉	Melting Point	>105°C (dec.)
	MSDS	N/A	Flash Point	561.8ºC

Use of Aivlosin

Tylvalosin (Acetylisovaleryltylo?sin) is a broad-spectrum macrolide antibiotic that has antibacterial activity. Tylvalosin is an antiviral agent and can be used for PRRSV infection. . Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, relieves oxidative stress, and relieves acute lung injury by suppression of NF-κB activation[1][2].

Name	Tylvalosin
Synonym	More Synonyms

Description	Tylvalosin (Acetylisovaleryltylo?sin) is a broad-spectrum macrolide antibiotic that has antibacterial activity. Tylvalosin is an antiviral agent and can be used for PRRSV infection. . Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, relieves oxidative stress, and relieves acute lung injury by suppression of NF-κB activation[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Albert Philip Adrian Mockett, et al. Use of tylvalosin as antiviral agent. Patent. WO2008007104. [2]. Zhao Z, et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. Biochem Pharmacol. 2014 Jul 1;90(1):73-87. [3]. Moges R, et al. Anti-Inflammatory Benefits of Antibiotics: Tylvalosin Induces Apoptosis of Porcine Neutrophils and Macrophages, Promotes Efferocytosis, and Inhibits Pro-Inflammatory CXCL-8, IL1α, and LTB4 Production, While Inducing the Release of Pro-Resolving Lipoxin A4 and Resolvin D1. Front Vet Sci. 2018 Apr 11;5:57.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Albert Philip Adrian Mockett, et al. Use of tylvalosin as antiviral agent. Patent. WO2008007104.

[2]. Zhao Z, et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. Biochem Pharmacol. 2014 Jul 1;90(1):73-87.

[3]. Moges R, et al. Anti-Inflammatory Benefits of Antibiotics: Tylvalosin Induces Apoptosis of Porcine Neutrophils and Macrophages, Promotes Efferocytosis, and Inhibits Pro-Inflammatory CXCL-8, IL1α, and LTB4 Production, While Inducing the Release of Pro-Resolving Lipoxin A4 and Resolvin D1. Front Vet Sci. 2018 Apr 11;5:57.

Density	1.21g/cm3
Boiling Point	1005.4ºC at 760 mmHg
Melting Point	>105°C (dec.)
Molecular Formula	C₅₃H₈₇NO₁₉
Molecular Weight	1042.25
Flash Point	561.8ºC
Exact Mass	1041.59000
PSA	250.81000
LogP	4.00130
Index of Refraction	1.534

2',3,4'''-tri-O...

CAS#:122825-66-5

~52%

Aivlosin

CAS#:63409-12-1

Literature: Fishman, Andrew G.; Mallams, Alan K.; Rossman, Randall R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 787 - 798

2',3,4'''-tri-O...

CAS#:122825-66-5

~45%

3-deoxy-4''-O-i...

CAS#:122825-69-8

Aivlosin

CAS#:63409-12-1