Asperphenamate
Modify Date: 2026-07-01 22:00:05
Asperphenamate structure
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Common Name | Asperphenamate | ||
|---|---|---|---|---|
| CAS Number | 63631-36-7 | Molecular Weight | 506.59200 | |
| Density | 1.198g/cm3 | Boiling Point | 774.3ºC at 760 mmHg | |
| Molecular Formula | C32H30N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 422.1ºC | |
Use of AsperphenamateAsperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively[1][2]. |
| Name | asperphenamate |
|---|---|
| Synonym | More Synonyms |
| Description | Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively[1][2]. |
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| Related Catalog | |
| In Vitro | Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S. |
| References |
[1]. Alice M.Clark, et al. Synthesis of asperphenamate, a novel fungal metabolite. Phytochemistry |
| Density | 1.198g/cm3 |
|---|---|
| Boiling Point | 774.3ºC at 760 mmHg |
| Molecular Formula | C32H30N2O4 |
| Molecular Weight | 506.59200 |
| Flash Point | 422.1ºC |
| Exact Mass | 506.22100 |
| PSA | 84.50000 |
| LogP | 5.39400 |
| Index of Refraction | 1.611 |
| InChIKey | CVULDJMCSSACEO-VMPREFPWSA-N |
| SMILES | O=C(NC(COC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)Cc1ccccc1)c1ccccc1 |
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Name: Antiproliferative activity against human HeLa cells after 3 days by MTT assay
Source: ChEMBL
Target: HeLa
External Id: CHEMBL1958685
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Name: Antiproliferative activity against human MCF7 cells after 3 days by MTT assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL1958684
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Name: Antiproliferative activity against human Bel7402 cells after 3 days by MTT assay
Source: ChEMBL
Target: Bel-7402
External Id: CHEMBL1958686
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Name: Antioxidant activity assessed as DPPH-radical scavenging activity
Source: ChEMBL
Target: N/A
External Id: CHEMBL974693
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Name: Thermodynamic solubility of the compound in phosphate buffer at pH 7.4 at 1 mg after ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1958708
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