TMPD dihydrochloride

Modify Date: 2024-01-11 10:20:14

TMPD dihydrochloride structure	Common Name	TMPD dihydrochloride
	CAS Number	637-01-4	Molecular Weight	237.169
	Density	N/A	Boiling Point	260.6ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₈Cl₂N₂	Melting Point	222-224 °C(lit.)
	MSDS	Chinese USA	Flash Point	104.9ºC
	Symbol	GHS07	Signal Word	Warning

Use of TMPD dihydrochloride

TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].

Name	N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
Synonym	More Synonyms

Description	TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	TMPD (N,N,N′,N′-tetramethyl-para-phenylene-diamine) is used in cell culture and microbiology to differentiate organisms that exhibit cytochrome c oxidase activity and to distinguish between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. The concept of TMPD oxidation by microorganisms is widely used and is known as a successful colorimetric indicator for bacterial oxidases, as the radical cation TMPD+˙, formed by oxidation, shows a characteristic deep blue colour. The electrochemical recognition of the TMPD oxidation by bacterial oxidases can be applied to a variety of pathogens[1].
References	[1]. S Kuss, et al. Electrochemical recognition and quantification of cytochrome c expression in Bacillus subtilis and aerobe/anaerobe Escherichia coli using N, N, N', N'-tetramethyl- para-phenylene-diamine (TMPD). Chem Sci. 2017 Nov 1;8(11):7682-7688. [2]. Nenad Petrovic, et al. Using N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro. Methods Mol Biol. 2010;594:129-40. [3]. Franco A Rossato, et al. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration. PLoS One. 2014 Jun 25;9(6):e101060.

Boiling Point	260.6ºC at 760 mmHg
Melting Point	222-224 °C(lit.)
Molecular Formula	C₁₀H₁₈Cl₂N₂
Molecular Weight	237.169
Flash Point	104.9ºC
Exact Mass	236.084702
PSA	6.48000
LogP	3.42260
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility	SOLUBLE

TMPD dihydrochloride MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S26-S36-S36/37
RIDADR	2811
WGK Germany	3
Packaging Group	II
Hazard Class	6.1(a)
HS Code	29215190

Wurster's blue

CAS#:100-22-1

TMPD dihydrochloride

CAS#:637-01-4

Literature: Journal of Physical Chemistry, , vol. 95, # 16 p. 6218 - 6227

HS Code	2921519090
Summary	2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

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1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine,dihydrochloride

MFCD00012482

N,N,N',N'-Tetramethylbenzol-1,4-diamindihydrochlorid

1,4-Benzenediamine, N,N,N,N-tetramethyl-, hydrochloride (1:2)

Wurster's reagent dihydrochloride

N,N,N',N'-Tetramethyl-P-phenylenediaminedihydrochloride

1,4-Benzenediamine, N,N,N',N'-tetramethyl-, dihydrochloride

N,N,N',N'-Tetramethylbenzene-1,4-diamine dihydrochloride

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EINECS 211-274-8

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: TMPD dihydrochloride
Price: ￥198.0/5g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: TMPD dihydrochloride
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 637-01-4 N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride C10H18Cl2N2
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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