HepIn-13
Modify Date: 2024-01-10 09:36:07
HepIn-13 structure
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Common Name | HepIn-13 | ||
|---|---|---|---|---|
| CAS Number | 64369-13-7 | Molecular Weight | 325.20300 | |
| Density | 1.444g/cm3 | Boiling Point | 533.3ºC at 760 mmHg | |
| Molecular Formula | C17H13BrN2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 276.4ºC | |
Use of HepIn-13Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer[1]. |
| Name | 2-(4-Brom-phenyl)-2,3-dihydro-1H-perimidin |
|---|---|
| Synonym | More Synonyms |
| Description | Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 0.33 μM (Hepsin) |
| In Vitro | Hepln-13 (10 µM; 2 hours; 293 cells) inhibits cleavage[1]. Western Blot Analysis[1] Cell Line: 293 cells Concentration: 10 µM Incubation Time: 2 hours Result: Inhibited cleavage. |
| In Vivo | HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis[1]. |
| References |
| Density | 1.444g/cm3 |
|---|---|
| Boiling Point | 533.3ºC at 760 mmHg |
| Molecular Formula | C17H13BrN2 |
| Molecular Weight | 325.20300 |
| Flash Point | 276.4ºC |
| Exact Mass | 324.02600 |
| PSA | 24.06000 |
| LogP | 5.41450 |
| Index of Refraction | 1.688 |
| Precursor 2 | |
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| DownStream 0 | |
| 1h-naphth[1,2-e][1,3]oxazine,2-(4-bromophenyl)-2,3-dihydro |
| 2-(4-bromo-phenyl)-2,3-dihydro-1H-perimidine |
| 2-<4-Brom-phenyl>-2.3-dihydro-1H-naphth<1.2-e>-1.3-oxazin |
| 2-(4-bromo-phenyl)-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazine |
| 2-(4-bromophenyl)-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazine |