Isoforskolin structure
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Common Name | Isoforskolin | ||
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CAS Number | 64657-21-2 | Molecular Weight | 410.501 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 524.5±50.0 °C at 760 mmHg | |
Molecular Formula | C22H34O7 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 173.6±23.6 °C |
Use of IsoforskolinIsoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
Name | Coleonol B |
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Synonym | More Synonyms |
Description | Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
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Related Catalog | |
In Vitro | Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 524.5±50.0 °C at 760 mmHg |
Molecular Formula | C22H34O7 |
Molecular Weight | 410.501 |
Flash Point | 173.6±23.6 °C |
Exact Mass | 410.230438 |
PSA | 113.29000 |
LogP | 3.40 |
Vapour Pressure | 0.0±3.1 mmHg at 25°C |
Index of Refraction | 1.552 |
Storage condition | −20°C |
Precursor 0 | |
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DownStream 1 | |
Isoforskolin |
(3R,4aR,5S,6S,10S,10aR,10bS)-5,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-6-yl acetate |
1H-Naphtho[2,1-b]pyran-1-one, 6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,10S,10aR,10bS)- |
6-Acetyl-7-deacetylforskolin |