Isoforskolin

Modify Date: 2024-01-06 14:11:33

Isoforskolin Structure
Isoforskolin structure
Common Name Isoforskolin
CAS Number 64657-21-2 Molecular Weight 410.501
Density 1.2±0.1 g/cm3 Boiling Point 524.5±50.0 °C at 760 mmHg
Molecular Formula C22H34O7 Melting Point N/A
MSDS Chinese USA Flash Point 173.6±23.6 °C

 Use of Isoforskolin


Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].

 Names

Name Coleonol B
Synonym More Synonyms

 Isoforskolin Biological Activity

Description Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].
Related Catalog
In Vitro Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1].
References

[1]. Zhao H, et al. Isoforskolin downregulates proinflammatory responses induced by Borrelia burgdorferi basic membrane protein A.Exp Ther Med. 2017 Dec;14(6):5974-5980.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 524.5±50.0 °C at 760 mmHg
Molecular Formula C22H34O7
Molecular Weight 410.501
Flash Point 173.6±23.6 °C
Exact Mass 410.230438
PSA 113.29000
LogP 3.40
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.552
Storage condition −20°C

 Safety Information

Hazard Codes Xn
Risk Phrases 21
Safety Phrases 36
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Isoforskolin
(3R,4aR,5S,6S,10S,10aR,10bS)-5,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-6-yl acetate
1H-Naphtho[2,1-b]pyran-1-one, 6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,10S,10aR,10bS)-
6-Acetyl-7-deacetylforskolin
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Isoforskolin
  • Price: ¥1000.0/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng



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Price: ¥2290/1 mg

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