Butoconazole nitrate
Modify Date: 2025-08-21 09:25:48
Butoconazole nitrate structure
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Common Name | Butoconazole nitrate | ||
|---|---|---|---|---|
| CAS Number | 64872-77-1 | Molecular Weight | 474.789 | |
| Density | N/A | Boiling Point | 566.9ºC at 760 mmHg | |
| Molecular Formula | C19H18Cl3N3O3S | Melting Point | 159ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 296.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Butoconazole nitrateButoconazole nitrate is an anti-fungal agent.Target: Antifungalbutoconazole 1-BSR is an effective and safe alternative to longer-term therapy with miconazole nitrate (seven days) for vulvovaginal candidiasis [1]. A sustained-release (SR) bioadhesive vaginal cream (2% butoconazole nitrate) has incorporated VagiSite technology, a topical drug delivery system that allows SR of the drug [2]. |
| Name | butoconazole nitrate |
|---|---|
| Synonym | More Synonyms |
| Description | Butoconazole nitrate is an anti-fungal agent.Target: Antifungalbutoconazole 1-BSR is an effective and safe alternative to longer-term therapy with miconazole nitrate (seven days) for vulvovaginal candidiasis [1]. A sustained-release (SR) bioadhesive vaginal cream (2% butoconazole nitrate) has incorporated VagiSite technology, a topical drug delivery system that allows SR of the drug [2]. |
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| Related Catalog | |
| References |
| Boiling Point | 566.9ºC at 760 mmHg |
|---|---|
| Melting Point | 159ºC (dec.) |
| Molecular Formula | C19H18Cl3N3O3S |
| Molecular Weight | 474.789 |
| Flash Point | 296.7ºC |
| Exact Mass | 473.013458 |
| PSA | 109.17000 |
| LogP | 6.81250 |
| Storage condition | -20?C Freezer |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933290090 |
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Effects of terconazole and other azole antifungal agents on the sterol and carbohydrate composition of Candida albicans.
Diagn. Microbiol. Infect. Dis. 13(1) , 31-5, (1990) The effects of terconazole, a triazole antifungal, on the sterol and carbohydrate composition of Candida albicans was compared with that of three imidazoles: clotrimazole, miconazole, and butoconazole... |
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Effect of butoconazole nitrate cream and wax insert on the barrier property of contraceptive devices.
Am. J. Obstet. Gynecol. 158(4) , 1011-3, (1988) A new method was developed to assess the quality of the barrier property of several types of commonly used contraceptive devices (diaphragm, cervical cap, and condom). Our data showed that butoconazol... |
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Patient acceptance of prefilled disposable vaginal applicator.
Am. J. Obstet. Gynecol. 158(4) , 1006-8, (1988) Patient acceptance of a new, compact, prefilled disposable vaginal applicator was tested in an open study in which 2% butoconazole cream was used for the treatment of vulvovaginal candidiasis. Twenty ... |
| (2S)-1-[2-(2,6-Dichlorophenylthio)-4-(4-chlorophenyl)butyl]-1H-imidazole nitrate |
| Butoconazole Nitrate |
| MFCD00058159 |
| 1-{4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole nitrate |
| UNII:4805237NP5 |
| 1-{4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole nitrate (1:1) |
| 1H-Imidazole, 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-, nitrate |
| 1-{4-(4-chlorophényl)-2-[(2,6-dichlorophényl)sulfanyl]butyl}-1H-imidazole nitrate |
| 1H-Imidazole, 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-, nitrate (1:1) |
| (2R)-1-[2-(2,6-Dichlorophenylthio)-4-(4-chlorophenyl)butyl]-1H-imidazole nitrate |