Jedi2
Modify Date: 2024-01-03 06:28:28
Jedi2 structure
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Common Name | Jedi2 | ||
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| CAS Number | 651005-90-2 | Molecular Weight | 208.23400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H8O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Jedi2Jedi2 is a Piezo1 channel activator, but no specific Piezo2 activators. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770 μM[1]. |
| Name | 2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid |
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| Synonym | More Synonyms |
| Description | Jedi2 is a Piezo1 channel activator, but no specific Piezo2 activators. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770 μM[1]. |
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| Related Catalog | |
| In Vitro | Jedi2 evokes Piezo1-mediated Ca2+ influx. Jedi2 (200 μM) specifically elicits dose-dependent responses in mPiezo1-transfected cells, but not in mPiezo2- or vector-transfected cells [1]. Jedi2 (1 mM) causes an increase in Ca2+ in mCherry-positive HEK293T cells transfected with the mPiezo1-mCherry construct, which also responded to Yoda1 (30 μM) [1]. |
| References |
| Molecular Formula | C10H8O3S |
|---|---|
| Molecular Weight | 208.23400 |
| Exact Mass | 208.01900 |
| PSA | 78.68000 |
| LogP | 3.01470 |
| Hazard Codes | Xn |
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| hms1431a19 |