Sulfinalol
Modify Date: 2024-01-04 17:50:29
Sulfinalol structure
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Common Name | Sulfinalol | ||
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| CAS Number | 66264-77-5 | Molecular Weight | 377.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H27NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SulfinalolSulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity[1]. |
| Name | 4-[1-hydroxy-2-[4-(4-methoxyphenyl)butan-2-ylamino]ethyl]-2-methylsulfinylphenol |
|---|---|
| Synonym | More Synonyms |
| Description | Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity[1]. |
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| Related Catalog | |
| Target |
β-adrenoceptor |
| In Vivo | Sulfinalol shows direct vasodilator activity and antihypertensive activity[1]. Animal Model: Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)[1] Dosage: 0-100 µg Administration: Intraarterial injection Result: Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs. Animal Model: Male spontaneously hypertensive rats (SHR)[1] Dosage: 2.5 mg/kg Administration: Oral administration Result: Reduced pressure of conscious spontaneously hypertensive rats. |
| References |
| Molecular Formula | C20H27NO4S |
|---|---|
| Molecular Weight | 377.50 |
| Exact Mass | 377.16600 |
| PSA | 98.00000 |
| LogP | 4.03910 |
| SULFINALOL |
| Sulfinalolum |