Dihydroguaiaretic acid

Modify Date: 2024-01-05 08:07:28

Dihydroguaiaretic acid Structure
Dihydroguaiaretic acid structure
Common Name Dihydroguaiaretic acid
CAS Number 66322-34-7 Molecular Weight 330.418
Density 1.1±0.1 g/cm3 Boiling Point 488.3±40.0 °C at 760 mmHg
Molecular Formula C20H26O4 Melting Point N/A
MSDS N/A Flash Point 249.1±27.3 °C

 Use of Dihydroguaiaretic acid


Dihydroguaiaretic acid, is isolated from the fruits of Schisandra chinensis with an anti-cancer activty[1].

 Names

Name 4-[(2R,3S)-4-(4-Hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-met hoxyphenol
Synonym More Synonyms

 Dihydroguaiaretic acid Biological Activity

Description Dihydroguaiaretic acid, is isolated from the fruits of Schisandra chinensis with an anti-cancer activty[1].
Related Catalog
In Vitro Dihydroguaiaretic acid shows inhibitory effect on Human ovarian cancer cells and A2780 Human endometrial cancer cells Ishikawa with IC50 values of 27.17 μM and 45.46 μM, respectively[1].
References

[1]. Arch Pharm Res. 2017 Apr;40(4):500-508. doi: 10.1007/s12272-017-0902-5. Epub 2017 Feb 22.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 488.3±40.0 °C at 760 mmHg
Molecular Formula C20H26O4
Molecular Weight 330.418
Flash Point 249.1±27.3 °C
Exact Mass 330.183105
PSA 58.92000
LogP 4.33
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.564

 Safety Information

Hazard Codes Xi

 Synonyms

Tetrahydrothebaine
Dihydroguaiaretic acid
4,4'-dihydroxy-3,3'-dimethoxylignan
4,5alpha-Epoxy-3,6-dimethoxy-17-methylmorphinan
4-[(2R,3S)-4-(4-Hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol
Phenol, 4-[(2R,3S)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxy-
meso-4,4'-dihydroxy-3,3'-dimethoxylignane
meso-dihydroguaiaretic acid
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