2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine structure
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Common Name | 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine | ||
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CAS Number | 66356-53-4 | Molecular Weight | 214.328 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 292.9±40.0 °C at 760 mmHg | |
Molecular Formula | C10H18N2OS | Melting Point | 96-97 °C(lit.) | |
MSDS | N/A | Flash Point | 130.9±27.3 °C |
Name | Ranitidine Impurity B |
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Synonym | More Synonyms |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 292.9±40.0 °C at 760 mmHg |
Melting Point | 96-97 °C(lit.) |
Molecular Formula | C10H18N2OS |
Molecular Weight | 214.328 |
Flash Point | 130.9±27.3 °C |
Exact Mass | 214.113983 |
PSA | 67.70000 |
LogP | 0.83 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.548 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 66356-53-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H18N2OS Molecular Weight: 214 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, acrid smoke and fumes. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 66356-53-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, N.O.S.* Hazard Class: 8 UN Number: 1760 Packing Group: III IMO Shipping Name: CORROSIVE LIQUID, N.O.S. Hazard Class: 8 UN Number: 1760 Packing Group: III RID/ADR Shipping Name: CORROSIVE LIQUID, N.O.S. Hazard Class: 8 UN Number: 1760 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 66356-53-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 66356-53-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 66356-53-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | C:Corrosive |
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Risk Phrases | R34 |
Safety Phrases | S26-S36/37/39-S45 |
RIDADR | 2735 |
HS Code | 2932190090 |
~70% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Navarro; Almeida; Anaya; Moran; Grande; Caballero; Palacios; Montero; San Roman Pharmazie, 1995 , vol. 50, # 1 p. 12 - 15 |
~66% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Chachula, Stanislaw; Grynkiewicz, Grzegorz; Szczycinski, Bohdan Polish Journal of Chemistry, 1990 , vol. 64, # 7 p. 619 - 622 |
~94% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Mascal, Mark; Dutta, Saikat Green Chemistry, 2011 , vol. 13, # 11 p. 3101 - 3102 |
~% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Polish Journal of Chemistry, , vol. 64, # 7 p. 619 - 622 |
~% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Pharmazie, , vol. 50, # 1 p. 12 - 15 |
~% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Green Chemistry, , vol. 13, # 11 p. 3101 - 3102 |
~% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Green Chemistry, , vol. 13, # 11 p. 3101 - 3102 |
~% 2-[([5-[(Dimeth... CAS#:66356-53-4 |
Literature: Polish Journal of Chemistry, , vol. 64, # 7 p. 619 - 622 |
Precursor 9 | |
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DownStream 10 | |
HS Code | 2932190090 |
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Summary | 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
EINECS 266-330-4 |
2-[({5-[(Dimethylamino)methyl]-2-furyl}methyl)sulfanyl]ethanamine |
5-((2-aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine |
2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethanamine |
2-(2-Aminoethylthiomethyl)-5-dimethylaminomethylfuran |
2-(5-Dimethylaminomethyl-furan-2-yl methylsulfanyl)-ethylamine |
MFCD00277202 |
2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine |
2-Furanmethanamine, 5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl- |
5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furfurylamine |
2-[[[5-(dimethylamine)methyl-2-furrny]methyl]thio]ethanamine; (Ranitidine intermediate) |
2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine |