CL 218872

Modify Date: 2024-01-17 13:00:56

CL 218872 Structure
CL 218872 structure
Common Name CL 218872
CAS Number 66548-69-4 Molecular Weight 278.23300
Density 1.43g/cm3 Boiling Point N/A
Molecular Formula C13H9F3N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL 218872


CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo[1].

 Names

Name 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
Synonym More Synonyms

 CL 218872 Biological Activity

Description CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo[1].
Related Catalog
References

[1]. Squires RF, et al. Some properties of brain specific benzodiazepine receptors: new evidence for multiple receptors. Pharmacol Biochem Behav. 1979 May;10(5):825-30.

 Chemical & Physical Properties

Density 1.43g/cm3
Molecular Formula C13H9F3N4
Molecular Weight 278.23300
Exact Mass 278.07800
PSA 43.08000
LogP 3.11850
Index of Refraction 1.615
Storage condition -20°C

 Synonyms

CL 218,872
Tocris-1709
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