N-ω-Acetylhistamine

Modify Date: 2025-08-25 11:59:06

N-ω-Acetylhistamine Structure
N-ω-Acetylhistamine structure
Common Name N-ω-Acetylhistamine
CAS Number 673-49-4 Molecular Weight 153.18200
Density 1.153g/cm3 Boiling Point 501.7ºC at 760 mmHg
Molecular Formula C7H11N3O Melting Point 147-149ºC(lit.)
MSDS Chinese USA Flash Point 257.2ºC

 Use of N-ω-Acetylhistamine


N-acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.

 Names

Name N-acetylhistamine
Synonym More Synonyms

 N-ω-Acetylhistamine Biological Activity

Description N-acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
Related Catalog
In Vitro N-acetylhistamine is an important indice for anaphylactoid reactions[1].
References

[1]. Xu Y, et al. Metabolomics analysis of anaphylactoid reaction reveals its mechanism in a rat model. Asian Pac J Allergy Immunol. 2017 Dec;35(4):224-232.

 Chemical & Physical Properties

Density 1.153g/cm3
Boiling Point 501.7ºC at 760 mmHg
Melting Point 147-149ºC(lit.)
Molecular Formula C7H11N3O
Molecular Weight 153.18200
Flash Point 257.2ºC
Exact Mass 153.09000
PSA 57.78000
LogP 0.47920
Index of Refraction 1.533
InChIKey XJWPISBUKWZALE-UHFFFAOYSA-N
SMILES CC(=O)NCCc1cnc[nH]1
Storage condition 2-8℃

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
HS Code 2933290090

 Synthetic Route

~%

N-ω-Acetylhistamine Structure

N-ω-Acetylhistamine

CAS#:673-49-4

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 177, p. 305

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles6

More Articles
[Oscillographic polarography of the alkaloid dolicotheline and several related imidazole derivatives].

Farmakol. Toksikol. 44(2) , 220-4, (1981)

Oscillographic polarography in an alkaline medium has shown that the alkaloid N-isovalerylhistamine appears as an expressive wave of the adsorption character in the cathode portion of the curve. This ...

Monooxygenation of N-acetylhistamine mediated by L-ascorbate.

Biochim. Biophys. Acta 991(2) , 377-9, (1989)

In the presence of molecular oxygen and a catalytic amount of copper(II) ion, ascorbate almost completely degraded histamine (approx. 72%). The reaction was shown to occur at the imidazole group but n...

Effects of intracerebroventricular administration of N-acetylhistamine on body temperature in mice.

Methods Find. Exp. Clin. Pharmacol. 16(8) , 575-81, (1994)

The purpose of this study was to examine the effects of intracerebroventricular (i.c.v.) administration of N-acetylhistamine on rectal temperature, histamine level, histidine decarboxylase (HDC) activ...

 N-ω-AcetylhistamineBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: QC Inhibition Testing from Article 10.1074/jbc.M309077200: "Identification of human g...
Source: BindingDB
Target: N/A
External Id: BindingDB_996_1
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

EINECS 211-610-3
Nomega-Acetylhistamine
N'-Acetylhistamine
N-[2-(1H-imidazol-5-yl)ethyl]acetamide
N-[2-(1H-Imidazol-4-yl)ethyl]acetamide
MFCD00005209
4-(2-acetamidoethyl)imidazole
Nw-acetyl-histamine
Acetylhistamine
N-ω-Acetylhistamine
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