3-(Cyclopentyloxy)-4-methoxybenzaldehyde

Modify Date: 2024-01-02 19:03:18

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure
3-(Cyclopentyloxy)-4-methoxybenzaldehyde structure
Common Name 3-(Cyclopentyloxy)-4-methoxybenzaldehyde
CAS Number 67387-76-2 Molecular Weight 220.264
Density 1.1±0.1 g/cm3 Boiling Point 351.9±22.0 °C at 760 mmHg
Molecular Formula C13H16O3 Melting Point 107-110℃ (ethyl acetate )
MSDS N/A Flash Point 157.9±8.8 °C

 Names

Name 3-(Cyclopentyloxy)-4-methoxybenzaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 351.9±22.0 °C at 760 mmHg
Melting Point 107-110℃ (ethyl acetate )
Molecular Formula C13H16O3
Molecular Weight 220.264
Flash Point 157.9±8.8 °C
Exact Mass 220.109940
PSA 35.53000
LogP 3.11
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.561

 MSDS

Name: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde 97% Material Safety Data Sheet
Synonym:
CAS: 67387-76-2
Section 1 - Chemical Product MSDS Name:3-(Cyclopentyloxy)-4-methoxybenzaldehyde 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
67387-76-2 3-(Cyclopentyloxy)-4-methoxybenzaldehy 97% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 67387-76-2: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Viscous liquid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 124 - 126 deg C @0mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C13H16O3
Molecular Weight: 220.27

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, bases, acids.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67387-76-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-(Cyclopentyloxy)-4-methoxybenzaldehyde - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 67387-76-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 67387-76-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67387-76-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-37/39
HS Code 2912499000

 Synthetic Route

~10%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: Brackeen, Marcus F.; Cowan, David J.; Stafford, Jeffrey A.; Schoenen, Frank J.; Veal, James M.; et al. Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4848 - 4854

~97%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: SmithKline Beecham Corporation Patent: US6337408 B1, 2002 ; Location in patent: Example 1 ;

~78%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: Kim, Euikyung; Chun, Hyung-Ok; Jung, Sung-Hak; Kim, Jong Hoon; Lee, Jae-Mok; Suh, Byung-Chul; Xiang, Myung Xik; Rhee, Chung K. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 14 p. 2355 - 2358

~%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: US4971959 A1, ;

~68%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: Li, Ke; Hu, Naifu; Luo, Renshi; Yuan, Weicheng; Tang, Wenjun Journal of Organic Chemistry, 2013 , vol. 78, # 12 p. 6350 - 6355

~%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 16 p. 2149 - 2152

~%

3-(Cyclopentyloxy)-4-methoxybenzaldehyde Structure

3-(Cyclopentylo...

CAS#:67387-76-2

Literature: Bioorganic and medicinal chemistry letters, , vol. 12, # 11 p. 1457 - 1461

 Customs

HS Code 2912499000
Summary 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

3-cyclopentyloxy-4-methoxybenzaldehyde
3-(Cyclopentyloxy)-4-methoxybenzaldehyde
MFCD00673136
Benzaldehyde, 3-(cyclopentyloxy)-4-methoxy-