1-Acetyl-4-(4-hydroxyphenyl)-piperazine structure
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Common Name | 1-Acetyl-4-(4-hydroxyphenyl)-piperazine | ||
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CAS Number | 67914-60-7 | Molecular Weight | 220.268 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 456.5±40.0 °C at 760 mmHg | |
Molecular Formula | C12H16N2O2 | Melting Point | 180-185 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 229.9±27.3 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Name | 4-(1-Acetylpiperazin-4-yl)Phenol |
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Synonym | More Synonyms |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 456.5±40.0 °C at 760 mmHg |
Melting Point | 180-185 °C(lit.) |
Molecular Formula | C12H16N2O2 |
Molecular Weight | 220.268 |
Flash Point | 229.9±27.3 °C |
Exact Mass | 220.121185 |
PSA | 43.78000 |
LogP | 0.19 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.585 |
Storage condition | -20°C Freezer |
Water Solubility | 4.3 g/L (20 ºC) |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful |
Risk Phrases | R22;R36/37/38 |
Safety Phrases | S26-S36-S36/37/39-S22 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933599090 |
~55% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: GALAPAGOS N.V. Patent: WO2008/55959 A1, 2008 ; Location in patent: Page/Page column 67 ; WO 2008/055959 A1 |
~92% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: Stefancich; Artico; Ortar; Silvestri; Simonetti; Apuzzo Archiv der Pharmazie, 1992 , vol. 325, # 11 p. 687 - 694 |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: US4435399 A1, ; |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: US4144346 A1, ; |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: Archiv der Pharmazie, , vol. 325, # 11 p. 687 - 694 |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 4 p. 887 - 890 |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: Archiv der Pharmazie, , vol. 325, # 11 p. 687 - 694 |
~% 1-Acetyl-4-(4-h... CAS#:67914-60-7 |
Literature: Journal of Heterocyclic Chemistry, , vol. 27, # 7 p. 2063 - 2068 |
Precursor 8 | |
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DownStream 3 | |
HS Code | 2933599090 |
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Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
General approach for electrochemical detection of persistent pharmaceutical micropollutants: Application to acetaminophen.
Biosens. Bioelectron. 72 , 205-10, (2015) We propose in this work a general and versatile methodology for electrochemical monitoring of persistent pharmaceutical micropollutants. The system presented is based on an electroactive and electropo... |
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New process for synthesis of 1-acetyl-4-(4-hydroxyphenyl) piperazine [J]. Zheng, CZ, et al.
Huaxue Shiji 10 , 27, (2010)
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Design of new potent and selective secretory phospholipase A2 inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives. Meddad-Belhabich N, et al.
Bioorg. Med. Chem. 18(10) , 3588-3600, (2010)
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1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone |
ethanone, 1-4-(4-hydroxyphenyl)-1-piperazinyl- |
1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone |
EINECS 267-744-8 |
1-4-(4-hydroxyphenyl)piperazin-1-ylethanone |
MFCD00044905 |
Ethanone, 1-[4-(4-hydroxyphenyl)-1-piperazinyl]- |
1-Acetyl-4-(4-hydroxyphenyl)-piperazine |
1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanon |