5-Ethynyl uridine
5-Ethynyl uridine structure
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Common Name | 5-Ethynyl uridine | ||
|---|---|---|---|---|
| CAS Number | 69075-42-9 | Molecular Weight | 268.22300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H12N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 5-Ethynyl uridine5-Ethynyluridine (5-EU) is a potent cell-permeable nucleoside can be used to label newly synthesized RNA. 5-Ethynyluridine can be used for isolation and sequencing of nascent RNA from neuronal populations in vivo. 5-Ethynyluridine can be used to identify changes in transcription in vivo in nervous system disease models[1][2]. |
| Name | 5-ethynyluridine |
|---|---|
| Synonym | More Synonyms |
| Description | 5-Ethynyluridine (5-EU) is a potent cell-permeable nucleoside can be used to label newly synthesized RNA. 5-Ethynyluridine can be used for isolation and sequencing of nascent RNA from neuronal populations in vivo. 5-Ethynyluridine can be used to identify changes in transcription in vivo in nervous system disease models[1][2]. |
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| Related Catalog | |
| In Vivo | 5-Ethynyluridine (75 mM in PBS for 1 µl; intracerebellar injection ) shows a labeling of central nervous system cells in mouse[1]. 5-Ethynyluridine (330-750 µMol/g; i.p.) results in in labelling of nascent RNA in cells of multiple organs and tissues, but not in the central nervous system in mouse[1]. |
| References |
| Molecular Formula | C11H12N2O6 |
|---|---|
| Molecular Weight | 268.22300 |
| Exact Mass | 268.07000 |
| PSA | 124.78000 |
| InChIKey | QCWBIPKYTBFWHH-FDDDBJFASA-N |
| SMILES | C#Cc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O |
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5-Ethynyl uridine CAS#:69075-42-9 |
| Literature: Chemical Communications, , vol. 49, # 30 p. 3128 - 3130 |
|
~%
5-Ethynyl uridine CAS#:69075-42-9 |
| Literature: Chemical Communications, , vol. 49, # 30 p. 3128 - 3130 |
|
~%
5-Ethynyl uridine CAS#:69075-42-9 |
| Literature: Chemical Communications, , vol. 49, # 30 p. 3128 - 3130 |
|
~%
5-Ethynyl uridine CAS#:69075-42-9 |
| Literature: Chemical Communications, , vol. 49, # 30 p. 3128 - 3130 |
|
~%
5-Ethynyl uridine CAS#:69075-42-9 |
| Literature: Chemical Communications, , vol. 49, # 30 p. 3128 - 3130 |
![2',3',5'-O-triacetyl-5-[(trimethylsilyl)ethynyl]-uridine structure](https://image.chemsrc.com/caspic/013/140914-90-5.png)
| 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione |
| 5-ETHYNYL URIDINE |