2,2,2-Trichloroethoxysulfonamide

Modify Date: 2024-01-08 11:00:49

2,2,2-Trichloroethoxysulfonamide Structure
2,2,2-Trichloroethoxysulfonamide structure
Common Name 2,2,2-Trichloroethoxysulfonamide
CAS Number 69226-51-3 Molecular Weight 228.48200
Density 1.801g/cm3 Boiling Point 288.7ºC at 760 mmHg
Molecular Formula C2H4Cl3NO3S Melting Point 56 °C
MSDS Chinese USA Flash Point 128.4ºC

 Names

Name 2,2,2-trichloroethyl sulfamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.801g/cm3
Boiling Point 288.7ºC at 760 mmHg
Melting Point 56 °C
Molecular Formula C2H4Cl3NO3S
Molecular Weight 228.48200
Flash Point 128.4ºC
Exact Mass 226.89800
PSA 77.77000
LogP 2.35780
Index of Refraction 1.543

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WO6200000
CHEMICAL NAME :
Sulfamic acid, 2,2,2-trichloroethyl ester
CAS REGISTRY NUMBER :
69226-51-3
LAST UPDATED :
199012
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C2-H4-Cl3-N-O3-S
MOLECULAR WEIGHT :
228.48
WISWESSER LINE NOTATION :
ZSWO1XGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MECHAN Medicinal Chemistry, A Series of Reviews. (New York, NY) V.1-6, 1951-63. Discontinued. Volume(issue)/page/year: 6,223,1963

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS WO6200000

 Synthetic Route

~88%

2,2,2-Trichloroethoxysulfonamide Structure

2,2,2-Trichloro...

CAS#:69226-51-3

Literature: Fiori, Kristin Williams; Du Bois Journal of the American Chemical Society, 2007 , vol. 129, # 3 p. 562 - 568

~52%

2,2,2-Trichloroethoxysulfonamide Structure

2,2,2-Trichloro...

CAS#:69226-51-3

Literature: Yamamoto, Hirofumi; Ho, Elisabeth; Sasaki, Ikuo; Mitsutake, Mizuho; Takagi, Yuichi; Imagawa, Hiroshi; Nishizawa, Mugio European Journal of Organic Chemistry, 2011 , # 13 p. 2417 - 2420

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2,2,2-Trichloroethoxysulfonamide Structure

2,2,2-Trichloro...

CAS#:69226-51-3

Literature: Sbihi; Beji; Baklouti Journal of Fluorine Chemistry, 2002 , vol. 115, # 2 p. 161 - 164

~%

2,2,2-Trichloroethoxysulfonamide Structure

2,2,2-Trichloro...

CAS#:69226-51-3

Literature: Bess, Elizabeth N.; Deluca, Ryan J.; Tindall, Daniel J.; Oderinde, Martins S.; Roizen, Jennifer L.; Du Bois; Sigman, Matthew S. Journal of the American Chemical Society, 2014 , vol. 136, # 15 p. 5783 - 5789

 Articles1

More Articles
Catalytic intermolecular amination of C-H bonds: method development and mechanistic insights.

J. Am. Chem. Soc. 129 , 562, (2007)

Reaction methodology for intermolecular C-H amination of benzylic and 3 degrees C-H bonds is described. This process uses the starting alkane as the limiting reagent, gives optically pure tetrasubstit...

 Synonyms

sulfamate de trichloro-2,2,2 ethyle
CCl3CH2OSO2NH2
2,2,2-trichloroethoxysulfonyl amine
1,1,1-trichloroethylsulfamate ester
2,2,2-Trichloroethoxysulfonamide
Sulfamic acid,2,2,2-trichloroethyl ester
2,2,2,3',4'-PENTAFLUOROACETOPHENONE