8-O-乙酰哈巴苷

• 常用名: 8-O-乙酰哈巴苷
• 英文名: 8-O-Acetylharpagide
• CAS号: 6926-14-3
• 分子量: 406.382
• 密度: 1.6±0.1 g/cm3
• 沸点: 607.2±55.0 °C at 760 mmHg
• 分子式: C₁₇H₂₆O₁₁
• 熔点: 227-229℃
• 闪点: 215.9±25.0 °C

8-O-乙酰哈巴苷用途

8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜化合物,具有抗肿瘤、抗病毒、抗菌和抗炎活性。8-O-Acetylharpagide 对豚鼠离体平滑肌也有生物活性。

8-O-乙酰哈巴苷名称

• 中文名: 乙酰哈巴苷
• 英文名: 8-O-Acetylharpagide
• 中文别名: 8-O-乙酰哈巴苷

8-O-乙酰哈巴苷生物活性

• 描述: 8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜化合物,具有抗肿瘤、抗病毒、抗菌和抗炎活性。8-O-Acetylharpagide 对豚鼠离体平滑肌也有生物活性。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8.

  [2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8.

8-O-乙酰哈巴苷物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 607.2±55.0 °C at 760 mmHg
• 熔点: 227-229℃
• 分子式: C₁₇H₂₆O₁₁
• 分子量: 406.382
• 闪点: 215.9±25.0 °C
• 精确质量: 406.147522
• PSA: 175.37000
• LogP: -3.48
• InChIKey: CAFTUQNGDROXEZ-XBDCZORHSA-N
• SMILES: CC(=O)OC1(C)CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12
• 蒸汽压: 0.0±3.9 mmHg at 25°C
• 折射率: 1.624
• 储存条件: ?20°C

8-O-乙酰哈巴苷安全信息

• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport

8-O-乙酰哈巴苷靶点实验

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8-O-乙酰哈巴苷英文别名

• β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-1-yl
• 6-Thio-8-propylthiotheophylline
• (1S,4aS,5R,7S,7aS)-1-(β-D-Glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl acetate
• 8-O-acetyl-harpagide
• Harpagide 7-acetyl
• Uric acid,1,3-dimethyl-8-propylthio-6-thio
• 8-n-Propylthio-6-thiotheophyllin