3-Iodo-L-tyrosine

Modify Date: 2026-07-03 12:12:13

3-Iodo-L-tyrosine Structure
3-Iodo-L-tyrosine structure
Common Name 3-Iodo-L-tyrosine
CAS Number 70-78-0 Molecular Weight 307.085
Density 1.9±0.1 g/cm3 Boiling Point 391.0±42.0 °C at 760 mmHg
Molecular Formula C9H10INO3 Melting Point 210 °C (dec.)(lit.)
MSDS USA Flash Point 190.3±27.9 °C

 Use of 3-Iodo-L-tyrosine


H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.

 Names

Name 3-iodo-L-tyrosine
Synonym More Synonyms

 3-Iodo-L-tyrosine Biological Activity

Description H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1].
References

[1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 391.0±42.0 °C at 760 mmHg
Melting Point 210 °C (dec.)(lit.)
Molecular Formula C9H10INO3
Molecular Weight 307.085
Flash Point 190.3±27.9 °C
Exact Mass 306.970520
PSA 83.55000
LogP 1.54
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.689
InChIKey UQTZMGFTRHFAAM-ZETCQYMHSA-N
SMILES NC(Cc1ccc(O)c(I)c1)C(=O)O
Storage condition 2-8°C
Water Solubility dilute aqueous acid: soluble

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 3-Iodo-L-tyrosineBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2...
Source: NCGC
Target: ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id: UBCH001
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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 Synonyms

3-Iodotyrosine
EINECS 200-744-8
3-IODO-L-TYROSINE
MFCD00002608
Monoiodotyrosine
3-Monoiodo-L-tyrosine
H-Tyr(3-I)-OH
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